{"id":159264,"date":"2023-02-28T23:25:38","date_gmt":"2023-03-01T05:25:38","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/02\/hiv-reservoirs-found-to-be-established-earlier-than-expected"},"modified":"2023-02-28T23:25:38","modified_gmt":"2023-03-01T05:25:38","slug":"hiv-reservoirs-found-to-be-established-earlier-than-expected","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/02\/hiv-reservoirs-found-to-be-established-earlier-than-expected","title":{"rendered":"HIV reservoirs found to be established earlier than expected"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/hiv-reservoirs-found-to-be-established-earlier-than-expected2.jpg\"><\/a><\/p>\n<p>For the first time in humans, a research team has shown that, as early as the first days of infection, HIV is able to create reservoirs where it will hide and persist during antiretroviral therapy.<\/p>\n<p>Until now, the scientific community did not know exactly when or how these viral reservoirs\u2014the existence of which is a major obstacle to curing HIV\u2014are established in human beings.<\/p>\n<p>In a study published in the journal <i>Immunity<\/i>, scientists led by Nicolas Chomont, a researcher at the CHUM Research Centre (CRCHUM) and professor at Universit\u00e9 de Montr\u00e9al, found that a small fraction of the <a href=\"https:\/\/medicalxpress.com\/tags\/virus\/\" rel=\"tag\" class=\"\">virus<\/a> integrates into the genome of CD4+ T cells in the very first weeks of <a href=\"https:\/\/medicalxpress.com\/tags\/infection\/\" rel=\"tag\" class=\"\">infection<\/a> (the acute phase), but does not replicate there. It therefore escapes the notice of the fastest diagnostic tool to date, which detects active viral replication.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>For the first time in humans, a research team has shown that, as early as the first days of infection, HIV is able to create reservoirs where it will hide and persist during antiretroviral therapy. Until now, the scientific community did not know exactly when or how these viral reservoirs\u2014the existence of which is a [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-159264","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/159264","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=159264"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/159264\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=159264"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=159264"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=159264"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}