{"id":159228,"date":"2023-02-28T15:25:37","date_gmt":"2023-02-28T21:25:37","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/02\/social-deficits-and-seizures-in-autism-genetic-subtype-tied-to-overexcited-brain-circuits"},"modified":"2023-02-28T15:25:37","modified_gmt":"2023-02-28T21:25:37","slug":"social-deficits-and-seizures-in-autism-genetic-subtype-tied-to-overexcited-brain-circuits","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/02\/social-deficits-and-seizures-in-autism-genetic-subtype-tied-to-overexcited-brain-circuits","title":{"rendered":"Social deficits and seizures in autism genetic subtype tied to overexcited brain circuits"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/social-deficits-and-seizures-in-autism-genetic-subtype-tied-to-overexcited-brain-circuits2.jpg\"><\/a><\/p>\n<p>Northwestern Medicine scientists have identified the cause of a genetic subtype of autism and schizophrenia that results in social deficits and seizures in mice and humans.<\/p>\n<p>Scientists have discovered a key feature of this subtype is a duplicated gene that results in overactive or overexcited brain circuits. The subtype is called 16p11.2 duplication syndrome.<\/p>\n<p>\u201cWe found that mice with the same <a href=\"https:\/\/medicalxpress.com\/tags\/genetic+changes\/\" rel=\"tag\" class=\"\">genetic changes<\/a> found in humans are more likely to have <a href=\"https:\/\/medicalxpress.com\/tags\/seizures\/\" rel=\"tag\" class=\"\">seizures<\/a> and also have <a href=\"https:\/\/medicalxpress.com\/tags\/social+deficits\/\" rel=\"tag\" class=\"\">social deficits<\/a>,\u201d said lead author Marc Forrest, research assistant professor of neuroscience at Northwestern University Feinberg School of Medicine.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Northwestern Medicine scientists have identified the cause of a genetic subtype of autism and schizophrenia that results in social deficits and seizures in mice and humans. Scientists have discovered a key feature of this subtype is a duplicated gene that results in overactive or overexcited brain circuits. The subtype is called 16p11.2 duplication syndrome. \u201cWe [\u2026]<\/p>\n","protected":false},"author":630,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-159228","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/159228","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/630"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=159228"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/159228\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=159228"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=159228"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=159228"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}