{"id":159188,"date":"2023-02-28T03:23:00","date_gmt":"2023-02-28T09:23:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/02\/dead-zone-within-tumor-promotes-cancer-spread-helped-by-a-protein-secreted-by-cancer-cells"},"modified":"2023-02-28T03:23:00","modified_gmt":"2023-02-28T09:23:00","slug":"dead-zone-within-tumor-promotes-cancer-spread-helped-by-a-protein-secreted-by-cancer-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/02\/dead-zone-within-tumor-promotes-cancer-spread-helped-by-a-protein-secreted-by-cancer-cells","title":{"rendered":"\u2018Dead zone\u2019 within tumor promotes cancer spread, helped by a protein secreted by cancer cells"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/sSBnwXis3VI?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>A tumor\u2019s necrotic core contains factors that appear to promote metastasis, or the seeding of tumors cells throughout the body, according to a new study in rats by researchers at Fred Hutchinson Cancer Center.<\/p>\n<p>Researchers hope their findings, which will be published the week of Feb. 27 in the <i>Proceedings of the National Academy of Sciences<\/i>, lead to a better understanding of how to cure metastatic, or stage 4 cancers, which are treatable but not curable.<\/p>\n<p>\u201cTumor necrotic cores are a fairly common phenomenon, but they haven\u2019t been linked to cancer metastasis until recently,\u201d said lead author Ami Yamamoto, a Fred Hutch graduate student working in the Cheung Lab. \u201cOur research put together observations other people have made into the specific context of breast cancer metastasis. Our work shows a link between necrosis, circulating <a href=\"https:\/\/medicalxpress.com\/tags\/tumor+cells\/\" rel=\"tag\" class=\"\">tumor cells<\/a> and cancer metastasis.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A tumor\u2019s necrotic core contains factors that appear to promote metastasis, or the seeding of tumors cells throughout the body, according to a new study in rats by researchers at Fred Hutchinson Cancer Center. Researchers hope their findings, which will be published the week of Feb. 27 in the Proceedings of the National Academy of [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-159188","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/159188","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=159188"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/159188\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=159188"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=159188"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=159188"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}