{"id":158865,"date":"2023-02-23T21:22:39","date_gmt":"2023-02-24T03:22:39","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/02\/feasibility-of-mapping-the-human-brain-with-expansion-x-ray-microscopy"},"modified":"2023-02-23T21:22:39","modified_gmt":"2023-02-24T03:22:39","slug":"feasibility-of-mapping-the-human-brain-with-expansion-x-ray-microscopy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/02\/feasibility-of-mapping-the-human-brain-with-expansion-x-ray-microscopy","title":{"rendered":"Feasibility of mapping the human brain with expansion x-ray microscopy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/feasibility-of-mapping-the-human-brain-with-expansion-x-ray-microscopy2.jpg\"><\/a><\/p>\n<p>Hey folks, I\u2019m excited to share a new essay with y\u2019all on my proposed route towards nanoscale human brain connectomics. I suggest that synchrotron \u2018expansion x-ray microscopy\u2019 has the potential to enable anatomical imaging of the entire human brain with sub-100 nm voxel size and high contrast in around 1 year for a price of roughly $10M. I plan to continue improving this essay over time as I acquire more detailed information and perform more calculations.<\/p>\n<p>For a brief history of this concept: I started exploring this idea during undergrad (working with a laboratory-scale x-ray microscope), but was cut short by the pandemic. Now, I\u2019m working on a PhD in biomedical engineering centered on gene therapy and synthetic biology, but I have retained a strong interest in connectomics. I recently began communication with some excellent collaborators who might be able to help move this technology forward. Hoping for some exciting progress!<\/p>\n<hr>\n<p>By Logan Thrasher Collins.<\/p>\n<p><center><strong><em>PDF version<\/em><\/strong><\/center><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hey folks, I\u2019m excited to share a new essay with y\u2019all on my proposed route towards nanoscale human brain connectomics. I suggest that synchrotron \u2018expansion x-ray microscopy\u2019 has the potential to enable anatomical imaging of the entire human brain with sub-100 nm voxel size and high contrast in around 1 year for a price of [\u2026]<\/p>\n","protected":false},"author":636,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,3,11,1965,4,47],"tags":[],"class_list":["post-158865","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biological","category-biotech-medical","category-mapping","category-nanotechnology","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/158865","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/636"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=158865"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/158865\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=158865"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=158865"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=158865"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}