{"id":158558,"date":"2023-02-20T14:23:36","date_gmt":"2023-02-20T20:23:36","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/02\/testing-their-strength-car-t-cells-combat-muscle-inflammation"},"modified":"2023-02-20T14:23:36","modified_gmt":"2023-02-20T20:23:36","slug":"testing-their-strength-car-t-cells-combat-muscle-inflammation","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/02\/testing-their-strength-car-t-cells-combat-muscle-inflammation","title":{"rendered":"Testing their strength: CAR T-cells combat muscle inflammation"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/testing-their-strength-car-t-cells-combat-muscle-inflammation.jpg\"><\/a><\/p>\n<p>Universit\u00e4tsklinikum Erlangen is the first in the world to use CAR T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The disease is triggered by a malfunction in the immune system that leads to inflammation of the muscles, and the risk of developing a very severe form of the disease is high. <i>The Lancet<\/i> has now published news of the successful treatment in a case report.<\/p>\n<p>When the 41 year old Mr. S. noticed a dramatic deterioration in this health last year, he initially put it down to a viral infection. However, his health took a dramatic turn for the worse when he was suddenly no longer to move more than a few feet and was barely able to stand up. His symptoms were caused by a severe autoimmune disease affecting his muscles, joints, skin and lungs belonging to the group of anti-immune muscle <a href=\"https:\/\/medicalxpress.com\/tags\/inflammatory+diseases\/\" rel=\"tag\" class=\"\">inflammatory diseases<\/a> (myositis). The diagnosis: anti-synthetase syndrome.<\/p>\n<p>The name anti-synthetase syndrome is derived from the observation that the enzymes required for the synthesis of amino acids known as aminoacyl-tRNA synthetases are attacked in error by the immune system. This severely impacts the function of various cells.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Universit\u00e4tsklinikum Erlangen is the first in the world to use CAR T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The disease is triggered by a malfunction in the immune system that leads to inflammation of the muscles, and the risk of developing a very severe form of the [\u2026]<\/p>\n","protected":false},"author":461,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-158558","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/158558","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/461"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=158558"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/158558\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=158558"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=158558"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=158558"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}