{"id":158021,"date":"2023-02-14T20:26:53","date_gmt":"2023-02-15T02:26:53","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/02\/will-crispr-cure-cancer"},"modified":"2023-02-14T20:26:53","modified_gmt":"2023-02-15T02:26:53","slug":"will-crispr-cure-cancer","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/02\/will-crispr-cure-cancer","title":{"rendered":"Will CRISPR Cure Cancer?"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/will-crispr-cure-cancer2.jpg\"><\/a><\/p>\n<p><em>One question for <\/em><a href=\"https:\/\/innovativegenomics.org\/people\/brad-ringeisen\/\" target=\"_blank\" aria-label=\" (opens in a new tab)\" rel=\"noreferrer noopener\" class=\"\"><em>Brad Ringeisen<\/em><\/a><em>, a chemist and executive director of the Innovative Genomics Institute. Founded by Nobel Prize-winning biochemist Jennifer Doudna, it aims to bridge revolutionary gene-editing tool development to affordable and accessible solutions in human health and climate.<\/em><\/p>\n<p><strong>Will CRISPR cure cancer?<\/strong><\/p>\n<p>We\u2019re always thinking about: What are those targets in the future? Cancer is one of those things. The biggest impact is going to be what\u2019s called systemic delivery, or in vivo delivery. There\u2019s been one example of this in the community right now\u2014to treat a liver disease. Intellia Therapeutics, a biotech company, has shown that you can actually intravenously apply CRISPR-Cas9 treatment. (CRISPR is the guide RNA, the targeting molecule, and Cas9 is the cutting molecule that edits DNA.) It can go to the liver and target the liver cells, and make edits at a high enough efficacy to treat genetic liver disease. The problem is that the liver is the easiest. It\u2019s like the garbage can of the body. Pretty much anything that you put into the body is ultimately going to find its way to the liver. So that\u2019s absolutely the easiest tissue to deliver to. But trying to deliver to a solid tumor, or to the brain, is much more difficult.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>One question for Brad Ringeisen, a chemist and executive director of the Innovative Genomics Institute. Founded by Nobel Prize-winning biochemist Jennifer Doudna, it aims to bridge revolutionary gene-editing tool development to affordable and accessible solutions in human health and climate. Will CRISPR cure cancer? We\u2019re always thinking about: What are those targets in the future? [\u2026]<\/p>\n","protected":false},"author":599,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,1495,47],"tags":[],"class_list":["post-158021","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/158021","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/599"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=158021"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/158021\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=158021"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=158021"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=158021"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}