{"id":156253,"date":"2023-01-25T19:26:53","date_gmt":"2023-01-26T01:26:53","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/01\/crisprs-wild-first-decade-only-scratches-the-surface-of-its-potential"},"modified":"2023-01-25T19:26:53","modified_gmt":"2023-01-26T01:26:53","slug":"crisprs-wild-first-decade-only-scratches-the-surface-of-its-potential","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/01\/crisprs-wild-first-decade-only-scratches-the-surface-of-its-potential","title":{"rendered":"CRISPR\u2019s Wild First Decade Only Scratches the Surface of Its Potential"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/crisprs-wild-first-decade-only-scratches-the-surface-of-its-potential.jpg\"><\/a><\/p>\n<p>You\u2019ve seen the headlines. The FDA approved its use in <a href=\"https:\/\/news.berkeley.edu\/2021\/03\/30\/fda-approves-first-test-of-crispr-to-correct-genetic-defect-causing-sickle-cell-disease\/\">tackling the underlying genetic mutation for sickle cell disease<\/a>. Some researchers <a href=\"https:\/\/www.gosh.nhs.uk\/news\/gosh-patient-receives-world-first-treatment-for-her-incurable-t-cell-leukaemia\/\">edited immune cells to fight untreatable blood cancers in children<\/a>. Others took <a href=\"https:\/\/www.nature.com\/articles\/d41586-022-00111-9\">pig-to-human organ transplants<\/a> from dream to reality in an attempt to alleviate the shortage of donor organs. Recent work aims to help millions of people with high cholesterol\u2014and potentially bring CRISPR-based gene therapy to the masses\u2014by <a href=\"https:\/\/singularityhub.com\/2022\/05\/16\/a-one-and-done-crispr-gene-therapy-will-aim-to-prevent-heart-attacks\/\">lowering their chances of heart disease<\/a> with a single injection.<\/p>\n<p>But to Dr. Jennifer Doudna, who won the Nobel Prize in 2020 for her role in developing CRISPR, we\u2019re just scratching the surface of its potential. Together with graduate student Joy Wang, Doudna laid out a roadmap for the technology\u2019s next decade <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.add8643\">in an article<\/a> in <em>Science<\/em>.<\/p>\n<p>If the 2010s were focused on establishing the CRISPR toolbox and proving its effectiveness, this decade is when the technology reaches its full potential. From CRISPR-based therapies and large-scale screens for disease diagnostics to engineering high-yield crops and nutritious foods, the technology \u201cand its potential impact are still in their early stages,\u201d the authors wrote.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>You\u2019ve seen the headlines. The FDA approved its use in tackling the underlying genetic mutation for sickle cell disease. Some researchers edited immune cells to fight untreatable blood cancers in children. Others took pig-to-human organ transplants from dream to reality in an attempt to alleviate the shortage of donor organs. Recent work aims to help [\u2026]<\/p>\n","protected":false},"author":599,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,1506,412],"tags":[],"class_list":["post-156253","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-food","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/156253","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/599"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=156253"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/156253\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=156253"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=156253"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=156253"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}