{"id":156133,"date":"2023-01-24T09:22:22","date_gmt":"2023-01-24T15:22:22","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/01\/genome-wide-rna-polymerase-stalling-shapes-the-transcriptome-during-aging-genetics"},"modified":"2023-01-24T09:22:22","modified_gmt":"2023-01-24T15:22:22","slug":"genome-wide-rna-polymerase-stalling-shapes-the-transcriptome-during-aging-genetics","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/01\/genome-wide-rna-polymerase-stalling-shapes-the-transcriptome-during-aging-genetics","title":{"rendered":"Genome-wide RNA polymerase stalling shapes the transcriptome during aging Genetics"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/genome-wide-rna-polymerase-stalling-shapes-the-transcriptome-during-aging-genetics.jpg\"><\/a><\/p>\n<p>In aging mouse livers, 40% of elongating RNA polymerases are stalled, biasing transcriptional output dependent on gene length. This transcriptional stress appears to be caused by endogenous DNA damage.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In aging mouse livers, 40% of elongating RNA polymerases are stalled, biasing transcriptional output dependent on gene length. This transcriptional stress appears to be caused by endogenous DNA damage.<\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-156133","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/156133","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=156133"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/156133\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=156133"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=156133"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=156133"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}