{"id":156070,"date":"2023-01-23T15:24:02","date_gmt":"2023-01-23T21:24:02","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/01\/dna-sequencing-method-can-detect-where-and-how-small-molecule-drugs-interact-with-their-targets"},"modified":"2023-01-23T15:24:02","modified_gmt":"2023-01-23T21:24:02","slug":"dna-sequencing-method-can-detect-where-and-how-small-molecule-drugs-interact-with-their-targets","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/01\/dna-sequencing-method-can-detect-where-and-how-small-molecule-drugs-interact-with-their-targets","title":{"rendered":"DNA sequencing method can detect where and how small molecule drugs interact with their targets"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/dna-sequencing-method-can-detect-where-and-how-small-molecule-drugs-interact-with-their-targets2.jpg\"><\/a><\/p>\n<p>Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work\u2014until now.<\/p>\n<p>In a paper published in the journal <i>Nature Biotechnology<\/i>, University of Cambridge researchers have outlined a new DNA sequencing method that can detect where and how small molecule drugs interact with the targeted genome.<\/p>\n<p>\u201cUnderstanding how drugs work in the body is essential to creating better, more <a href=\"https:\/\/phys.org\/tags\/effective+therapies\/\" rel=\"tag\" class=\"\">effective therapies<\/a>,\u201d said co-first author Dr. Zutao Yu from the Yusuf Hamied Department of Chemistry. \u201cBut when a therapeutic drug enters a cancer cell with a genome that has three billion bases, it\u2019s like entering a black box.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work\u2014until now. In a paper published in the journal Nature Biotechnology, University of Cambridge researchers have outlined a new DNA sequencing method that can detect where and how small molecule drugs interact [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-156070","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/156070","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=156070"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/156070\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=156070"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=156070"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=156070"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}