{"id":155186,"date":"2023-01-11T12:25:47","date_gmt":"2023-01-11T18:25:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/01\/scientists-just-reprogrammed-mice-to-live-longer-humans-may-be-next"},"modified":"2023-01-11T12:25:47","modified_gmt":"2023-01-11T18:25:47","slug":"scientists-just-reprogrammed-mice-to-live-longer-humans-may-be-next","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/01\/scientists-just-reprogrammed-mice-to-live-longer-humans-may-be-next","title":{"rendered":"Scientists Just Reprogrammed Mice to Live Longer. Humans May Be Next"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-just-reprogrammed-mice-to-live-longer-humans-may-be-next.jpg\"><\/a><\/p>\n<p>In the Rejuvenate Bio effort\u2014the company published a <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2023.01.04.522507v1.full\" target=\"_blank\" class=\"\">paper<\/a> that hasn\u2019t yet been peer-reviewed and was noted for a lack of documentation on which cells were changed\u2014the mice given the treatment were equivalent to a 77-year-old human (about 124 weeks old in mice years). The treated mice lived an extra 9 weeks, on average, beyond the control mice\u2014good for a 7 percent increase in life. The experiment also produced a near-immediate effect.<\/p>\n<p>\u201cThis is a powerful technology, and here is the proof of concept,\u201d Noah Davidohn, chief scientific officer of Rejuvenate, <a href=\"https:\/\/www.technologyreview.com\/2023\/01\/09\/1066488\/biotech-says-mice-live-longer-after-genetic-reprogramming\/\" target=\"_blank\" class=\"\">told<\/a> <em>MIT<\/em> <em>Technology Review<\/em>. \u201cI wanted to show that it\u2019s actually something we can do in our elderly population.\u201d<\/p>\n<p>Gene reprogramming is still a nascent\u2014and divisive\u2014field. Early research was, of course, limited to single cells. And mice have far fewer cells than a human. Expanding the concept to a human\u2014with the upside of a 7 percent increase in life expectancy as our initial benchmark, no less\u2014brings with it scale that increases risk.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the Rejuvenate Bio effort\u2014the company published a paper that hasn\u2019t yet been peer-reviewed and was noted for a lack of documentation on which cells were changed\u2014the mice given the treatment were equivalent to a 77-year-old human (about 124 weeks old in mice years). The treated mice lived an extra 9 weeks, on average, beyond [\u2026]<\/p>\n","protected":false},"author":599,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-155186","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/155186","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/599"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=155186"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/155186\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=155186"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=155186"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=155186"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}