{"id":154261,"date":"2023-01-03T14:22:38","date_gmt":"2023-01-03T20:22:38","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/01\/parkinsons-breakthrough-scientists-have-identified-a-key-molecule"},"modified":"2023-01-03T14:22:38","modified_gmt":"2023-01-03T20:22:38","slug":"parkinsons-breakthrough-scientists-have-identified-a-key-molecule","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/01\/parkinsons-breakthrough-scientists-have-identified-a-key-molecule","title":{"rendered":"Parkinson\u2019s Breakthrough: Scientists Have Identified a Key Molecule"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/parkinsons-breakthrough-scientists-have-identified-a-key-molecule2.jpg\"><\/a><\/p>\n<p>Adenosine, a neurotransmitter, has been found to act as a brake on dopamine, another neurotransmitter involved in motor control, by researchers at <a href=https:\/\/scitechdaily.com\/tag\/oregon-health-science-university\/>Oregon Health &amp; Science University<\/a>. The findings, which were published in the journal <em>Nature<\/em>, reveal that adenosine and dopamine operate in a push-pull dynamic in the brain.<\/p>\n<p>\u201cThere are two neuronal circuits: one that helps promote action and the other that inhibits action,\u201d said senior author Haining Zhong, Ph.D., a scientist with the OHSU Vollum Institute. \u201cDopamine promotes the first circuit to enable movement, and adenosine is the \u2018brake\u2019 that promotes the second circuit and brings balance to the system.\u201d<\/p>\n<p>The discovery has the potential to immediately suggest new avenues for drug development to treat the symptoms of Parkinson\u2019s disease is a movement disorder that is believed to be caused by the loss of dopamine-producing cells in the brain.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Adenosine, a neurotransmitter, has been found to act as a brake on dopamine, another neurotransmitter involved in motor control, by researchers at Oregon Health &amp; Science University. The findings, which were published in the journal Nature, reveal that adenosine and dopamine operate in a push-pull dynamic in the brain. \u201cThere are two neuronal circuits: one [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-154261","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/154261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=154261"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/154261\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=154261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=154261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=154261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}