{"id":154189,"date":"2023-01-02T14:22:50","date_gmt":"2023-01-02T20:22:50","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2023\/01\/new-method-precisely-locates-gene-activity-and-proteins-across-tissues"},"modified":"2023-01-02T14:22:50","modified_gmt":"2023-01-02T20:22:50","slug":"new-method-precisely-locates-gene-activity-and-proteins-across-tissues","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2023\/01\/new-method-precisely-locates-gene-activity-and-proteins-across-tissues","title":{"rendered":"New method precisely locates gene activity and proteins across tissues"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-method-precisely-locates-gene-activity-and-proteins-across-tissues2.jpg\"><\/a><\/p>\n<p>A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center.<\/p>\n<p>The method, described Jan. 2 in a paper in <i>Nature Biotechnology<\/i>, records gene activity patterns and the presence of key proteins in <a href=\"https:\/\/phys.org\/tags\/cells\/\" rel=\"tag\" class=\"\">cells<\/a> across <a href=\"https:\/\/phys.org\/tags\/tissue+samples\/\" rel=\"tag\" class=\"\">tissue samples<\/a>, while retaining information about the cells\u2019 precise locations. This enables the creation of complex, data-rich \u201cmaps\u201d of organs, including diseased organs and tumors, which could be widely useful in basic and <a href=\"https:\/\/phys.org\/tags\/clinical+research\/\" rel=\"tag\" class=\"\">clinical research<\/a>.<\/p>\n<p>\u201cThis technology is exciting because it allows us to map the spatial organization of tissues, including cell types, cell activities and cell-to-cell interactions, as never before,\u201d said study co-senior author Dr. Dan Landau, an associate professor of medicine in the Division of Hematology and Medical Oncology and a member of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine and a core faculty member at the New York Genome Center.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center. The method, described Jan. 2 in a paper in Nature Biotechnology, records gene activity patterns and the [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-154189","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/154189","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=154189"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/154189\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=154189"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=154189"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=154189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}