{"id":153239,"date":"2022-12-19T19:31:40","date_gmt":"2022-12-20T01:31:40","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/12\/stresses-and-hydrodynamics-scientists-uncover-new-organizing-principles-of-the-genome"},"modified":"2022-12-19T19:31:40","modified_gmt":"2022-12-20T01:31:40","slug":"stresses-and-hydrodynamics-scientists-uncover-new-organizing-principles-of-the-genome","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/12\/stresses-and-hydrodynamics-scientists-uncover-new-organizing-principles-of-the-genome","title":{"rendered":"Stresses and hydrodynamics: Scientists uncover new organizing principles of the genome"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/1PlLLcauMbc?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>A team of scientists has uncovered the physical principles\u2014a series of forces and hydrodynamic flows\u2014that help ensure the proper functioning of life\u2019s blueprint. Its discovery provides new insights into the genome while potentially offering a new means to spot genomic aberrations linked to developmental disorders and human diseases.<\/p>\n<p>\u201cThe way in which the <a href=\"https:\/\/phys.org\/tags\/genome\/\" rel=\"tag\" class=\"\">genome<\/a> is organized and packed inside the nucleus directly affects its biological function, yet the physical principles behind this organization are far from understood,\u201d explains Alexandra Zidovska, an associate professor in New York University\u2019s Department of Physics and an author of the paper, which appears in the journal <i>Physical Review X<\/i> (<i>PRX<\/i>). \u201cOur results provide fundamental insights into the biophysical origins of the organization of the genome inside the <a href=\"https:\/\/phys.org\/tags\/cell+nucleus\/\" rel=\"tag\" class=\"\">cell nucleus<\/a>.\u201d<\/p>\n<p>\u201cSuch knowledge is crucial for understanding the genome\u2019s function,\u201d adds David Saintillan, a professor at the University of California San Diego\u2019s Department of Mechanical and Aerospace Engineering and an author of the paper.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of scientists has uncovered the physical principles\u2014a series of forces and hydrodynamic flows\u2014that help ensure the proper functioning of life\u2019s blueprint. Its discovery provides new insights into the genome while potentially offering a new means to spot genomic aberrations linked to developmental disorders and human diseases. \u201cThe way in which the genome is [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11],"tags":[],"class_list":["post-153239","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/153239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=153239"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/153239\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=153239"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=153239"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=153239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}