{"id":153086,"date":"2022-12-18T01:22:20","date_gmt":"2022-12-18T07:22:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/12\/a-change-of-heart-cellular-reprogramming-reverses-fibrosis-after-heart-attack"},"modified":"2022-12-18T01:22:20","modified_gmt":"2022-12-18T07:22:20","slug":"a-change-of-heart-cellular-reprogramming-reverses-fibrosis-after-heart-attack","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/12\/a-change-of-heart-cellular-reprogramming-reverses-fibrosis-after-heart-attack","title":{"rendered":"A change of heart? Cellular reprogramming reverses fibrosis after heart attack"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-change-of-heart-cellular-reprogramming-reverses-fibrosis-after-heart-attack2.jpg\"><\/a><\/p>\n<p>Researchers from Japan reveal that they may just have found a way to repair cardiac damage in patients suffering from chronic heart attack and heart failure.<\/p>\n<p>In a study published in <i>Circulation<\/i>, researchers from the University of Tsukuba have shown that changing heart cell programming by tweaking the expression of a few key genes can actually reverse the lasting damage caused by heart attacks.<\/p>\n<p>Adult heart cells have very limited ability to form new heart tissue, so when the <a href=\"https:\/\/medicalxpress.com\/tags\/heart+muscle\/\" rel=\"tag\" class=\"\">heart muscle<\/a> is damaged by a <a href=\"https:\/\/medicalxpress.com\/tags\/heart+attack\/\" rel=\"tag\" class=\"\">heart attack<\/a>, the damaged areas are filled in with inflexible scar tissue. The presence of scar tissue impairs <a href=\"https:\/\/medicalxpress.com\/tags\/heart+function\/\" rel=\"tag\" class=\"\">heart function<\/a> and leads to arrhythmias, progressive <a href=\"https:\/\/medicalxpress.com\/tags\/heart+failure\/\" rel=\"tag\" class=\"\">heart failure<\/a> and eventual death.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from Japan reveal that they may just have found a way to repair cardiac damage in patients suffering from chronic heart attack and heart failure. In a study published in Circulation, researchers from the University of Tsukuba have shown that changing heart cell programming by tweaking the expression of a few key genes can [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-153086","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/153086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=153086"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/153086\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=153086"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=153086"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=153086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}