{"id":153008,"date":"2022-12-17T05:22:59","date_gmt":"2022-12-17T11:22:59","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/12\/atomic-structure-of-a-staphylococcal-bacteriophage-using-cryo-electron-microscopy"},"modified":"2022-12-17T05:22:59","modified_gmt":"2022-12-17T11:22:59","slug":"atomic-structure-of-a-staphylococcal-bacteriophage-using-cryo-electron-microscopy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/12\/atomic-structure-of-a-staphylococcal-bacteriophage-using-cryo-electron-microscopy","title":{"rendered":"Atomic structure of a staphylococcal bacteriophage using cryo-electron microscopy"},"content":{"rendered":"<p><a class=\"blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/atomic-structure-of-a-staphylococcal-bacteriophage-using-cryo-electron-microscopy2.jpg\"><\/a><\/p>\n<p>Cryo-electron microscopy by University of Alabama at Birmingham researchers has exposed the structure of a bacterial virus with unprecedented detail. This is the first structure of a virus able to infect Staphylococcus epidermidis, and high-resolution knowledge of structure is a key link between viral biology and potential therapeutic use of the virus to quell bacterial infections.<\/p>\n<p>Bacteriophages or \u201cphages\u201d is the terms used for viruses that infect bacteria. The UAB researchers, led by Terje Dokland, Ph.D., in collaboration with Asma Hatoum-Aslan, Ph.D., at the University of Illinois Urbana-Champaign, have described atomic models for all or part of 11 different structural proteins in phage Andhra. The <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.ade0459\">study is published<\/a> in Science Advances.<\/p>\n<p>Andhra is a member of the picovirus group. Its host range is limited to S. epidermidis. This skin bacterium is mostly benign but also is a leading cause of infections of indwelling medical devices. \u201cPicoviruses are rarely found in phage collections and remain understudied and underused for therapeutic applications,\u201d said Hatoum-Aslan, a phage biologist at the University of Illinois.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cryo-electron microscopy by University of Alabama at Birmingham researchers has exposed the structure of a bacterial virus with unprecedented detail. This is the first structure of a virus able to infect Staphylococcus epidermidis, and high-resolution knowledge of structure is a key link between viral biology and potential therapeutic use of the virus to quell bacterial [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-153008","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/153008","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=153008"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/153008\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=153008"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=153008"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=153008"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}