{"id":152175,"date":"2022-12-08T09:27:19","date_gmt":"2022-12-08T15:27:19","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/12\/a-signaling-pathway-within-brain-cells-that-regulates-how-long-and-how-deeply-we-sleep"},"modified":"2022-12-08T09:27:19","modified_gmt":"2022-12-08T15:27:19","slug":"a-signaling-pathway-within-brain-cells-that-regulates-how-long-and-how-deeply-we-sleep","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/12\/a-signaling-pathway-within-brain-cells-that-regulates-how-long-and-how-deeply-we-sleep","title":{"rendered":"A signaling pathway within brain cells that regulates how long and how deeply we sleep"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-signaling-pathway-within-brain-cells-that-regulates-how-long-and-how-deeply-we-sleep2.jpg\"><\/a><\/p>\n<p>A good night\u2019s sleep can work wonders for both mind and body. But what is it that determines how much we need to sleep, and what can cause us to sleep more deeply?<\/p>\n<p>In a new study, researchers from the University of Tsukuba have now provided some answers, revealing a signaling pathway within <a href=\"https:\/\/medicalxpress.com\/tags\/brain+cells\/\" rel=\"tag\" class=\"\">brain cells<\/a> that regulates the length and depth of sleep.<\/p>\n<p>\u201cWe examined <a href=\"https:\/\/medicalxpress.com\/tags\/genetic+mutations\/\" rel=\"tag\" class=\"\">genetic mutations<\/a> in mice and how these affect their patterns of sleep,\u201d says senior author of the study, Professor Hiromasa Funato. \u201cWe identified a mutation that led to the mice sleeping much longer and more deeply than usual.\u201d The researchers found that this was caused by low levels of an enzyme called histone deacetylase 4 (HDAC4), which is known to suppress the expression of target genes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A good night\u2019s sleep can work wonders for both mind and body. But what is it that determines how much we need to sleep, and what can cause us to sleep more deeply? In a new study, researchers from the University of Tsukuba have now provided some answers, revealing a signaling pathway within brain cells [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[412,47],"tags":[],"class_list":["post-152175","post","type-post","status-publish","format-standard","hentry","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/152175","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=152175"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/152175\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=152175"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=152175"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=152175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}