{"id":151646,"date":"2022-12-01T23:23:02","date_gmt":"2022-12-02T05:23:02","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/12\/new-genetic-mutation-behind-childhood-glaucoma-identified"},"modified":"2022-12-01T23:23:02","modified_gmt":"2022-12-02T05:23:02","slug":"new-genetic-mutation-behind-childhood-glaucoma-identified","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/12\/new-genetic-mutation-behind-childhood-glaucoma-identified","title":{"rendered":"New genetic mutation behind childhood glaucoma identified"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-genetic-mutation-behind-childhood-glaucoma-identified2.jpg\"><\/a><\/p>\n<p>The researchers discovered a mutation in the thrombospondin-1 (THBS1) gene in three ethnically and geographically diverse families with a history of childhood glaucoma using advanced genome-sequencing technology. The researchers then confirmed their findings in a mouse model that had the genetic mutation and developed <a target=\"_blank\" href=\"https:\/\/www.hindustantimes.com\/lifestyle\/glaucoma-awareness-month-ayurvedic-remedies-to-improve-eye-health-101642506613756.html\">glaucoma symptoms<\/a> due to a previously unknown disease mechanism.<\/p>\n<p>ALSO READ: <a target=\"_blank\" href=\"https:\/\/www.hindustantimes.com\/lifestyle\/health\/check-out-these-easy-eye-care-tips-to-keep-your-eyes-healthy-as-you-age-101661507031847.html\">Check out these easy eye care tips to keep your eyes healthy as you age<\/a><\/p>\n<p>This increase in pressure not only damages the optic nerve but can also affect other structures in a child\u2019s eye like the cornea. <a target=\"_blank\" href=\"https:\/\/www.hindustantimes.com\/lifestyle\/health\/heres-why-high-caffeine-consumption-may-cause-blinding-eye-disease-101623502767029.html\">Children with childhood glaucoma<\/a> typically require surgeries as early as the first three to six months of life, followed by several more operations throughout their childhood.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The researchers discovered a mutation in the thrombospondin-1 (THBS1) gene in three ethnically and geographically diverse families with a history of childhood glaucoma using advanced genome-sequencing technology. The researchers then confirmed their findings in a mouse model that had the genetic mutation and developed glaucoma symptoms due to a previously unknown disease mechanism. ALSO READ: [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-151646","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/151646","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=151646"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/151646\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=151646"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=151646"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=151646"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}