{"id":151388,"date":"2022-11-29T03:24:09","date_gmt":"2022-11-29T09:24:09","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/11\/chemotherapy-could-increase-disease-susceptibility-in-future-generations"},"modified":"2022-11-29T03:24:09","modified_gmt":"2022-11-29T09:24:09","slug":"chemotherapy-could-increase-disease-susceptibility-in-future-generations","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/11\/chemotherapy-could-increase-disease-susceptibility-in-future-generations","title":{"rendered":"Chemotherapy could increase disease susceptibility in future generations"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/chemotherapy-could-increase-disease-susceptibility-in-future-generations2.jpg\"><\/a><\/p>\n<p>A common chemotherapy drug could carry a toxic inheritance for children and grandchildren of adolescent cancer survivors, Washington State University-led research indicates.<\/p>\n<p>The study, published online in <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2589004222018429\">iScience<\/a>, found that male rats who received the <a href=\"https:\/\/medicalxpress.com\/tags\/drug\/\" rel=\"tag\" class=\"\">drug<\/a> ifosfamide during adolescence had offspring and grand-offspring with increased incidence of disease. While other research has shown that cancer treatments can increase patients\u2019 chance of developing disease later in life, this is one of the first-known studies showing that susceptibility can be passed down to a third generation of unexposed offspring.<\/p>\n<p>\u201cThe findings suggest that if a patient receives <a href=\"https:\/\/medicalxpress.com\/tags\/chemotherapy\/\" rel=\"tag\" class=\"\">chemotherapy<\/a>, and then later has children, that their grandchildren, and even great-grandchildren, may have an increased disease susceptibility due to their ancestors\u2019 chemotherapy exposure,\u201d said Michael Skinner, a WSU biologist and corresponding author on the study.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A common chemotherapy drug could carry a toxic inheritance for children and grandchildren of adolescent cancer survivors, Washington State University-led research indicates. The study, published online in iScience, found that male rats who received the drug ifosfamide during adolescence had offspring and grand-offspring with increased incidence of disease. While other research has shown that cancer [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,20],"tags":[],"class_list":["post-151388","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/151388","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=151388"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/151388\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=151388"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=151388"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=151388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}