{"id":149926,"date":"2022-11-11T13:22:20","date_gmt":"2022-11-11T19:22:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/11\/new-drug-reverses-neural-and-cognitive-effects-of-a-concussion"},"modified":"2022-11-11T13:22:20","modified_gmt":"2022-11-11T19:22:20","slug":"new-drug-reverses-neural-and-cognitive-effects-of-a-concussion","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/11\/new-drug-reverses-neural-and-cognitive-effects-of-a-concussion","title":{"rendered":"New Drug Reverses Neural and Cognitive Effects of a Concussion"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-drug-reverses-neural-and-cognitive-effects-of-a-concussion.jpg\"><\/a><\/p>\n<p>ISRIB, a tiny molecule identified by <a href=https:\/\/scitechdaily.com\/tag\/ucsf\/>University of California, San Francisco (UCSF)<\/a> researchers can repair the neural and cognitive effects of concussion in mice weeks after the damage, according to a new study.<\/p>\n<p>ISRIB blocks the integrated stress response (ISR), a quality control process for protein production that, when activated chronically, can be harmful to cells.<\/p>\n<p>The study, which was recently published in the <em>Proceedings of the National Academy of Sciences<\/em>, discovered that ISRIB reverses the effects of traumatic brain injury (TBI) on dendritic spines, an area of neurons vital to cognition. The drug-treated mice also showed sustained improvements in working memory.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>ISRIB, a tiny molecule identified by University of California, San Francisco (UCSF) researchers can repair the neural and cognitive effects of concussion in mice weeks after the damage, according to a new study. ISRIB blocks the integrated stress response (ISR), a quality control process for protein production that, when activated chronically, can be harmful to [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-149926","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/149926","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=149926"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/149926\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=149926"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=149926"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=149926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}