{"id":149363,"date":"2022-11-02T19:23:45","date_gmt":"2022-11-03T00:23:45","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/11\/a-new-look-at-the-role-of-nmda-in-brain-function-and-psychiatric-disorders"},"modified":"2022-11-02T19:23:45","modified_gmt":"2022-11-03T00:23:45","slug":"a-new-look-at-the-role-of-nmda-in-brain-function-and-psychiatric-disorders","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/11\/a-new-look-at-the-role-of-nmda-in-brain-function-and-psychiatric-disorders","title":{"rendered":"A new look at the role of NMDA in brain function and psychiatric disorders"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-new-look-at-the-role-of-nmda-in-brain-function-and-psychiatric-disorders2.jpg\"><\/a><\/p>\n<p>New images from scientists at Cold Spring Harbor Laboratory (CSHL) reveal for the first time the three-dimensional structures of a set of molecules critical for healthy brain function.<\/p>\n<p>The molecules are members of a family of proteins in the <a href=\"https:\/\/medicalxpress.com\/tags\/brain\/\" rel=\"tag\" class=\"\">brain<\/a> known as NMDA receptors, which mediate the passage of essential signals between neurons. The detailed pictures generated by the CSHL team will serve as a valuable blueprint for drug developers working on new treatments for schizophrenia, depression, and other neuropsychiatric conditions.<\/p>\n<p>\u201cThis NMDA receptor is such an important drug target,\u201d says Tsung-Han Chou, a postdoctoral researcher in CSHL Professor Hiro Furukawa\u2019s lab. That\u2019s because dysfunctional NMDA receptors are thought to contribute to a wide range of conditions, including not just depression and schizophrenia, but also Alzheimer\u2019s disease, stroke, and seizures. \u201cWe hope our images, which visualize the receptor for the first time, will facilitate <a href=\"https:\/\/medicalxpress.com\/tags\/drug+development\/\" rel=\"tag\" class=\"\">drug development<\/a> across the field based on our structural information,\u201d Chou says.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New images from scientists at Cold Spring Harbor Laboratory (CSHL) reveal for the first time the three-dimensional structures of a set of molecules critical for healthy brain function. The molecules are members of a family of proteins in the brain known as NMDA receptors, which mediate the passage of essential signals between neurons. The detailed [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-149363","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/149363","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=149363"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/149363\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=149363"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=149363"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=149363"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}