{"id":148342,"date":"2022-10-17T11:38:39","date_gmt":"2022-10-17T16:38:39","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/10\/near-limitless-crispr-therapies-this-drug-delivery-breakthrough-helps-gene-editing-technology-infiltrate-cells"},"modified":"2022-10-17T11:38:39","modified_gmt":"2022-10-17T16:38:39","slug":"near-limitless-crispr-therapies-this-drug-delivery-breakthrough-helps-gene-editing-technology-infiltrate-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/10\/near-limitless-crispr-therapies-this-drug-delivery-breakthrough-helps-gene-editing-technology-infiltrate-cells","title":{"rendered":"\u2018Near-limitless CRISPR therapies\u2019: This drug delivery breakthrough helps gene editing technology infiltrate cells"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/near-limitless-crispr-therapies-this-drug-delivery-breakthrough-helps-gene-editing-technology-infiltrate-cells.jpg\"><\/a><\/p>\n<p>A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics.<\/p>\n<p>Using chemical design and synthesis, the team brought together the Nobel-prize winning technology with therapeutic technology born in their own lab to overcome a critical limitation of CRISPR. Specifically, the groundbreaking work provides a system to deliver the cargo required for generating the gene editing machine known as CRISPR-Cas9. The team developed a way to transform the Cas-9 protein into a spherical <a class=\"\" href=\"https:\/\/www.news-medical.net\/life-sciences\/What-is-Nucleic-Acid.aspx\">nucleic acid<\/a> (SNA) and load it with critical components as required to access a broad range of tissue and cell types, as well as the intracellular compartments required for gene editing.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics. Using chemical design and synthesis, the team brought together the Nobel-prize winning technology with therapeutic technology born in their own lab to overcome a critical limitation of [\u2026]<\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,19],"tags":[],"class_list":["post-148342","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/148342","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=148342"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/148342\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=148342"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=148342"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=148342"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}