{"id":147905,"date":"2022-10-10T21:22:18","date_gmt":"2022-10-11T02:22:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/10\/aging-environment-and-genetics-which-is-more-important-for-regulating-gene-expression"},"modified":"2022-10-10T21:22:18","modified_gmt":"2022-10-11T02:22:18","slug":"aging-environment-and-genetics-which-is-more-important-for-regulating-gene-expression","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/10\/aging-environment-and-genetics-which-is-more-important-for-regulating-gene-expression","title":{"rendered":"Aging, Environment and Genetics: Which Is More Important for Regulating Gene Expression?"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/aging-environment-and-genetics-which-is-more-important-for-regulating-gene-expression.jpg\"><\/a><\/p>\n<p>Amid much speculation and research about how our genetics affect the way we age, a University of California, Berkeley, study now shows that individual differences in our DNA matter less as we get older and become prone to diseases of aging, such as diabetes and cancer.<\/p>\n<p>In a study of the relative effects of genetics, aging and the environment on how some 20,000 human genes are expressed, the researchers found that aging and environment are far more important than genetic variation in affecting the expression profiles of many of our genes as we get older. The level at which genes are expressed \u2014 that is, ratcheted up or down in activity \u2014 determines everything from our hormone levels and metabolism to the mobilization of enzymes that repair the body.<\/p>\n<p>\u201cHow do your genetics \u2014 what you got from your sperm donor and your egg donor and your evolutionary history \u2014 influence who you are, your phenotype, such as your height, your weight, whether or not you have heart disease?\u201d said Peter Sudmant, UC Berkeley assistant professor of integrative biology and a member of the campus\u2019s Center for Computational Biology. \u201cThere\u2019s been a huge amount of work done in human genetics to understand how genes are turned on and off by human genetic variation. Our project came about by asking, \u2018How is that influenced by an individual\u2019s age?\u2019 And the first result we found was that your genetics actually matter less the older you get.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Amid much speculation and research about how our genetics affect the way we age, a University of California, Berkeley, study now shows that individual differences in our DNA matter less as we get older and become prone to diseases of aging, such as diabetes and cancer. In a study of the relative effects of genetics, [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1523,412,269],"tags":[],"class_list":["post-147905","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-computing","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/147905","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=147905"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/147905\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=147905"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=147905"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=147905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}