{"id":147430,"date":"2022-10-03T05:22:18","date_gmt":"2022-10-03T10:22:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/10\/deep-stimulation-improves-cognitive-control"},"modified":"2022-10-03T05:22:18","modified_gmt":"2022-10-03T10:22:18","slug":"deep-stimulation-improves-cognitive-control","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/10\/deep-stimulation-improves-cognitive-control","title":{"rendered":"Deep stimulation improves cognitive control"},"content":{"rendered":"

<\/a><\/p>\n

In a new study that could improve the therapeutic efficacy of deep-brain stimulation (DBS) for psychiatric disorders such as depression, a team of scientists shows that, when DBS is applied to a specific brain region, it improves patients\u2019 cognitive control over their behavior by increasing the power of a specific low-frequency brain rhythm in their prefrontal cortex.<\/p>\n

The findings, published April 4 in Nature Communications<\/i>, suggest that the increase in \u201ctheta\u201d rhythms, readily detectable in EEG recordings, could provide neurosurgeons and psychiatrists with the reliable, objective and rapid feedback they\u2019ve needed to properly fine-tune the placement and \u201cdosage\u201d of DBS electrical stimulation. In Parkinson\u2019s disease, where DBS has been most successful, that kind of feedback is available through a reduction in a patient\u2019s tremors. But for depression or obsessive-compulsive disorder<\/a>, symptoms can be more subtle, subjective and slowly emergent.<\/p>\n

\u201cThis is a major step forward for psychiatric brain stimulation,\u201d said Alik Widge, the lead and corresponding author on the paper. Widge began the work while a clinical fellow at the Picower Institute for Learning and Memory at MIT and a research fellow at Massachusetts General Hospital (MGH). He is now an Assistant Professor of Psychiatry at the University of Minnesota Medical School. \u201cThis study shows us a specific mechanism of how DBS improves patients\u2019 brain function<\/a>, which should let us better identify who can benefit and how to optimize their individual treatment.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

In a new study that could improve the therapeutic efficacy of deep-brain stimulation (DBS) for psychiatric disorders such as depression, a team of scientists shows that, when DBS is applied to a specific brain region, it improves patients\u2019 cognitive control over their behavior by increasing the power of a specific low-frequency brain rhythm in their [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-147430","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/147430","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=147430"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/147430\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=147430"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=147430"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=147430"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}