{"id":146916,"date":"2022-09-24T01:25:24","date_gmt":"2022-09-24T06:25:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/09\/crispr-based-hiv-gene-therapy-administered-to-first-human-patient"},"modified":"2022-09-24T01:25:24","modified_gmt":"2022-09-24T06:25:24","slug":"crispr-based-hiv-gene-therapy-administered-to-first-human-patient","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/09\/crispr-based-hiv-gene-therapy-administered-to-first-human-patient","title":{"rendered":"CRISPR-Based HIV Gene Therapy Administered To First Human Patient"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/W24LFKL51NA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>In a clinical trial, the first patient has received a single dose of a new <a href=\"https:\/\/www.iflscience.com\/tags\/HIV\" rel=\"noopener noreferrer\" target=\"_blank\">human immunodeficiency virus (HIV)<\/a> gene editing therapy, researchers at the Lewis Katz School of Medicine at Temple University and Excision BioTherapeutics, Inc have reported.<\/p>\n<p>In a collaborative effort, the researchers are currently running a phase 1\/2 clinical trial to evaluate the safety and efficacy of their therapy, called <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT05144386\" rel=\"noopener noreferrer\" target=\"_blank\">EBT-101<\/a>, which is based on gene editing technology known as <a href=\"https:\/\/www.iflscience.com\/tags\/CRISPR\" rel=\"noopener noreferrer\" target=\"_blank\">CRISPR<\/a>.<\/p>\n<p>\u201cNearly 40 million people worldwide suffer from the effects of HIV, and more than 40 years after the discovery of HIV\/AIDS, there still are no curative treatments,\u201d said Professor Kamel Khalili, who helped lead the trial, in a <a href=\"https:\/\/www.eurekalert.org\/news-releases\/965472\" target=\"_blank\"> statement<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a clinical trial, the first patient has received a single dose of a new human immunodeficiency virus (HIV) gene editing therapy, researchers at the Lewis Katz School of Medicine at Temple University and Excision BioTherapeutics, Inc have reported. In a collaborative effort, the researchers are currently running a phase 1\/2 clinical trial to evaluate [\u2026]<\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11],"tags":[],"class_list":["post-146916","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/146916","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=146916"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/146916\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=146916"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=146916"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=146916"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}