{"id":146736,"date":"2022-09-20T21:02:51","date_gmt":"2022-09-21T02:02:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/09\/scientists-have-long-dreamed-of-a-memory-prosthesis-the-first-human-trials-look-promising"},"modified":"2022-09-20T21:02:51","modified_gmt":"2022-09-21T02:02:51","slug":"scientists-have-long-dreamed-of-a-memory-prosthesis-the-first-human-trials-look-promising","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/09\/scientists-have-long-dreamed-of-a-memory-prosthesis-the-first-human-trials-look-promising","title":{"rendered":"Scientists Have Long Dreamed of a Memory Prosthesis. The First Human Trials Look Promising"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-have-long-dreamed-of-a-memory-prosthesis-the-first-human-trials-look-promising3.jpg\"><\/a><\/p>\n<p>For the memory prosthetic, the team focused on two specific regions: CA1 and CA3, which form a highly interconnected neural circuit. Decades of work in rodents, primates, and humans have pointed to this neural highway as the crux for encoding memories.<\/p>\n<p>The team members, led by Drs. Dong Song from the University of Southern California and Robert Hampson at Wake Forest School of Medicine, are no strangers to memory prosthetics. With \u201cmemory bioengineer\u201d Dr. Theodore Berger\u2014who\u2019s worked on hijacking the CA3-CA1 circuit for memory improvement for over three decades\u2014the dream team had their first success in humans in 2015.<\/p>\n<p>The central idea is simple: replicate the hippocampus\u2019 signals with a digital <i>replace <\/i>ment. It\u2019s no easy task. Unlike computer circuits, neural circuits are non-linear. This means that signals are often extremely noisy and overlap in time, which bolsters\u2014or inhibits\u2014neural signals. As Berger said at the time: \u201cIt\u2019s a chaotic black box.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>For the memory prosthetic, the team focused on two specific regions: CA1 and CA3, which form a highly interconnected neural circuit. Decades of work in rodents, primates, and humans have pointed to this neural highway as the crux for encoding memories. The team members, led by Drs. Dong Song from the University of Southern California [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,1523,1499,47],"tags":[],"class_list":["post-146736","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-computing","category-cyborgs","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/146736","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=146736"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/146736\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=146736"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=146736"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=146736"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}