{"id":145737,"date":"2022-09-06T07:22:49","date_gmt":"2022-09-06T12:22:49","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/09\/scientists-find-that-the-loss-of-a-youth-protein-could-drive-aging"},"modified":"2022-09-06T07:22:49","modified_gmt":"2022-09-06T12:22:49","slug":"scientists-find-that-the-loss-of-a-youth-protein-could-drive-aging","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/09\/scientists-find-that-the-loss-of-a-youth-protein-could-drive-aging","title":{"rendered":"Scientists Find That the Loss of a \u201cYouth\u201d Protein Could Drive Aging"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-find-that-the-loss-of-a-youth-protein-could-drive-aging2.jpg\"><\/a><\/p>\n<p>Did they unlock one of the vital keys to stop aging?<\/p>\n<hr>\n<p>According to a recent National Eye Institute (NEI) study in mice, loss of the protein pigment epithelium-derived factor (PEDF), which protects retinal support cells, may promote age-related changes in the retina.<\/p>\n<p>Age-related retinal diseases, such as age-related macular degeneration (AMD), can cause blindness since the retina is the light-sensitive tissue at the back of the eye. The new information could help develop medicines to stop AMD and other aging conditions of the retina. The research was published in the <em>International Journal of Molecular Sciences<\/em>. NEI is part of the National Institutes of Health.<\/p>\n<p>\u201cPeople have called PEDF the \u2018youth\u2019 protein because it is abundant in young retinas, but it declines during aging,\u201d said Patricia Becerra, Ph.D., chief of NEI\u2019s Section of Protein Structure and Function and senior author of the study. \u201cThis study showed for the first time that just removing PEDF leads to a host of gene changes that mimic aging in the retina.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Did they unlock one of the vital keys to stop aging? According to a recent National Eye Institute (NEI) study in mice, loss of the protein pigment epithelium-derived factor (PEDF), which protects retinal support cells, may promote age-related changes in the retina. Age-related retinal diseases, such as age-related macular degeneration (AMD), can cause blindness since [\u2026]<\/p>\n","protected":false},"author":430,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-145737","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/145737","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/430"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=145737"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/145737\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=145737"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=145737"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=145737"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}