{"id":144260,"date":"2022-08-16T12:49:14","date_gmt":"2022-08-16T17:49:14","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/08\/smart-nanoparticle-shows-that-intermittent-fasting-may-protect-the-heart-from-damage-during-chemotherapy"},"modified":"2022-08-16T12:49:14","modified_gmt":"2022-08-16T17:49:14","slug":"smart-nanoparticle-shows-that-intermittent-fasting-may-protect-the-heart-from-damage-during-chemotherapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/08\/smart-nanoparticle-shows-that-intermittent-fasting-may-protect-the-heart-from-damage-during-chemotherapy","title":{"rendered":"Smart nanoparticle shows that intermittent fasting may protect the heart from damage during chemotherapy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/smart-nanoparticle-shows-that-intermittent-fasting-may-protect-the-heart-from-damage-during-chemotherapy3.jpg\"><\/a><\/p>\n<p>Although chemotherapy can be a lifesaving treatment for patients with cancer, some of these medications can damage the heart. A team led by researchers at Massachusetts General Hospital (MGH) recently developed a nanoparticle probe that can detect an indicator of heart damage from chemotherapy.<\/p>\n<p>Experiments with the probe also revealed that in mice with cancer, intermittent fasting before chemotherapy can prevent this <a href=\"https:\/\/phys.org\/tags\/heart\/\" rel=\"tag\" class=\"\">heart<\/a> damage indicator from arising, leading to preserved cardiac function and prolonged survival.<\/p>\n<p>The study, which is published in <i>Nature Biomedical Engineering<\/i>, focused on autophagy\u2014a process that cells use to remove unnecessary or dysfunctional components. A delicate balance exists between the protective and deleterious effects of this process: reduced levels of autophagy have been implicated in <a href=\"https:\/\/phys.org\/tags\/cardiovascular+disease\/\" rel=\"tag\" class=\"\">cardiovascular disease<\/a> and other conditions; however, autophagy can also be a primary mechanism of cell death.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Although chemotherapy can be a lifesaving treatment for patients with cancer, some of these medications can damage the heart. A team led by researchers at Massachusetts General Hospital (MGH) recently developed a nanoparticle probe that can detect an indicator of heart damage from chemotherapy. Experiments with the probe also revealed that in mice with cancer, [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,4],"tags":[],"class_list":["post-144260","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/144260","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=144260"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/144260\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=144260"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=144260"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=144260"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}