{"id":142945,"date":"2022-07-27T09:22:20","date_gmt":"2022-07-27T14:22:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/07\/research-shows-investigational-drug-fosters-nerve-repair-after-injury"},"modified":"2022-07-27T09:22:20","modified_gmt":"2022-07-27T14:22:20","slug":"research-shows-investigational-drug-fosters-nerve-repair-after-injury","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/07\/research-shows-investigational-drug-fosters-nerve-repair-after-injury","title":{"rendered":"Research shows investigational drug fosters nerve repair after injury"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/research-shows-investigational-drug-fosters-nerve-repair-after-injury2.jpg\"><\/a><\/p>\n<p>\ud835\udc11\ud835\udc1e\ud835\udc2c\ud835\udc1e\ud835\udc1a\ud835\udc2b\ud835\udc1c\ud835\udc21 \ud835\udc2c\ud835\udc21\ud835\udc28\ud835\udc30\ud835\udc2c \ud835\udc22\ud835\udc27\ud835\udc2f\ud835\udc1e\ud835\udc2c\ud835\udc2d\ud835\udc22\ud835\udc20\ud835\udc1a\ud835\udc2d\ud835\udc22\ud835\udc28\ud835\udc27\ud835\udc1a\ud835\udc25 \ud835\udc1d\ud835\udc2b\ud835\udc2e\ud835\udc20 \ud835\udc1f\ud835\udc28\ud835\udc2c\ud835\udc2d\ud835\udc1e\ud835\udc2b\ud835\udc2c \ud835\udc27\ud835\udc1e\ud835\udc2b\ud835\udc2f\ud835\udc1e \ud835\udc2b\ud835\udc1e\ud835\udc29\ud835\udc1a\ud835\udc22\ud835\udc2b \ud835\udc1a\ud835\udc1f\ud835\udc2d\ud835\udc1e\ud835\udc2b \ud835\udc22\ud835\udc27\ud835\udc23\ud835\udc2e\ud835\udc2b\ud835\udc32<\/p>\n<hr>\n<p>Scientists from the University of Birmingham have shown that a brain-penetrating candidate drug currently in development as a cancer therapy can foster regeneration of damaged nerves after spinal trauma.<\/p>\n<p>The <a href=\"https:\/\/medicalxpress.com\/tags\/research\/\" rel=\"tag\" class=\"\">research<\/a>, published today in <i>Clinical and Translational Medicine<\/i>, used cell and animal models to demonstrate that when taken orally the candidate drug, known as <a href=\"https:\/\/openinnovation.astrazeneca.com\/preclinical-research\/preclinical-molecules\/azd1390.html\">AZD1390<\/a>, can block the response to DNA damage in <a href=\"https:\/\/medicalxpress.com\/tags\/nerve+cells\/\" rel=\"tag\" class=\"\">nerve cells<\/a> and promote <a href=\"https:\/\/medicalxpress.com\/tags\/regeneration\/\" rel=\"tag\" class=\"\">regeneration<\/a> of damaged nerves, so restoring sensory and <a href=\"https:\/\/medicalxpress.com\/tags\/motor+function\/\" rel=\"tag\" class=\"\">motor function<\/a> after <a href=\"https:\/\/medicalxpress.com\/tags\/spinal+injury\/\" rel=\"tag\" class=\"\">spinal injury<\/a>.<\/p>\n<p>The announcement comes weeks after the same research team showed a <a <a href=\"https:\/\/medicalxpress.com\/news\/2022-05-spinal-cord-injury-treatment.html\"\">https:\/\/medicalxpress.com\/news\/2022&#45;05-spinal-cord-injury-treatment.html\"<\/a>&gt;different investigational drug<\/a> (AZD1236) can reduce damage after spinal cord injury, by blocking the inflammatory response. Both studies were supported by AstraZeneca\u2019s Open Innovations Program, which shares compounds, tools, technologies and expertise with the scientific community to advance drug discovery and development\u2026<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\ud835\udc11\ud835\udc1e\ud835\udc2c\ud835\udc1e\ud835\udc1a\ud835\udc2b\ud835\udc1c\ud835\udc21 \ud835\udc2c\ud835\udc21\ud835\udc28\ud835\udc30\ud835\udc2c \ud835\udc22\ud835\udc27\ud835\udc2f\ud835\udc1e\ud835\udc2c\ud835\udc2d\ud835\udc22\ud835\udc20\ud835\udc1a\ud835\udc2d\ud835\udc22\ud835\udc28\ud835\udc27\ud835\udc1a\ud835\udc25 \ud835\udc1d\ud835\udc2b\ud835\udc2e\ud835\udc20 \ud835\udc1f\ud835\udc28\ud835\udc2c\ud835\udc2d\ud835\udc1e\ud835\udc2b\ud835\udc2c \ud835\udc27\ud835\udc1e\ud835\udc2b\ud835\udc2f\ud835\udc1e \ud835\udc2b\ud835\udc1e\ud835\udc29\ud835\udc1a\ud835\udc22\ud835\udc2b \ud835\udc1a\ud835\udc1f\ud835\udc2d\ud835\udc1e\ud835\udc2b \ud835\udc22\ud835\udc27\ud835\udc23\ud835\udc2e\ud835\udc2b\ud835\udc32 Scientists from the University of Birmingham have shown that a brain-penetrating candidate drug currently in development as a cancer therapy can foster regeneration of damaged nerves after spinal trauma. The research, published today in Clinical and Translational Medicine, used cell and animal models to demonstrate that [\u2026]<\/p>\n","protected":false},"author":461,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-142945","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/142945","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/461"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=142945"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/142945\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=142945"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=142945"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=142945"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}