{"id":140917,"date":"2022-06-21T16:24:15","date_gmt":"2022-06-21T21:24:15","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/06\/patients-treated-with-crispr-still-cured-three-years-later"},"modified":"2022-06-21T16:24:15","modified_gmt":"2022-06-21T21:24:15","slug":"patients-treated-with-crispr-still-cured-three-years-later","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/06\/patients-treated-with-crispr-still-cured-three-years-later","title":{"rendered":"Patients Treated With CRISPR Still \u201cCured\u201d Three Years Later"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/patients-treated-with-crispr-still-cured-three-years-later2.jpg\"><\/a><\/p>\n<p>A long-running human trial has shown that CRISPR gene editing could prove to be a highly effective way of treating serious conditions.<\/p>\n<p>The trial, which was kicked off in 2019 by an international team of scientists, found that a new gene-editing therapy called exagamglogene autotemcel, or ex-cel for short, was able to essentially \u201ccure\u201d patients with transfusion-dependent beta thalassemia (TDT) or severe sickle cell disease (SCD), two blood disorders that are conventionally treated using blood transfusions.<\/p>\n<p>It\u2019s a promising new use of the technology. Around <a href=\"https:\/\/www.cdc.gov\/ncbddd\/sicklecell\/data.html#:~:text=SCD%20affects%20approximately%20100%2C000%20Americans, sickle%20cell%20trait%20(SCT).\" class=\"\">100,000 Americans<\/a> are affected by TDT, while SCD affects an <a href=\"https:\/\/rarediseases.info.nih.gov\/diseases\/871\/beta-thalassemia\" class=\"\">estimated 300 to 3,000<\/a>. And in a broader sense, the results suggest that tinkering with genetic code could come to be a practical, widespread new area of medicine.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A long-running human trial has shown that CRISPR gene editing could prove to be a highly effective way of treating serious conditions. The trial, which was kicked off in 2019 by an international team of scientists, found that a new gene-editing therapy called exagamglogene autotemcel, or ex-cel for short, was able to essentially \u201ccure\u201d patients [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-140917","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140917","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=140917"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140917\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=140917"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=140917"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=140917"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}