{"id":140845,"date":"2022-06-20T16:03:20","date_gmt":"2022-06-20T21:03:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/06\/mrna-treatment-repairs-mouse-hearts-to-near-normal-after-heart-attack"},"modified":"2022-06-20T16:03:20","modified_gmt":"2022-06-20T21:03:20","slug":"mrna-treatment-repairs-mouse-hearts-to-near-normal-after-heart-attack","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/06\/mrna-treatment-repairs-mouse-hearts-to-near-normal-after-heart-attack","title":{"rendered":"MRNA treatment repairs mouse hearts to \u201cnear normal\u201d after heart attack"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mrna-treatment-repairs-mouse-hearts-to-near-normal-after-heart-attack2.jpg\"><\/a><\/p>\n<p>Researchers at the University of Houston have demonstrated a new technique for helping heart cells regenerate after a heart attack, using mRNA to return the cells to a stem-cell-like state. Tests in mice showed drastic improvements to heart function a month after a heart attack.<\/p>\n<p>Unlike most tissues in the body, heart cells have a limited ability to regenerate after injury. That\u2019s a big part of why heart attacks are so deadly \u2013 afterwards, non-beating scar tissue forms instead, which can lead to further attacks and eventually heart failure.<\/p>\n<p>In recent years, scientists have been investigating how to repair broken hearts by regenerating the cells, with some success seen using <a class=\"\" href=\"https:\/\/newatlas.com\/placenta-stem-cells-repair-heart-attack\/59785\/\" data-cms-ai=\"0\">placental stem cells<\/a>, <a class=\"\" href=\"https:\/\/newatlas.com\/scientists-create-beating-heart-cells\/15994\/\" data-cms-ai=\"0\">reprogramming structural cells<\/a> into ones that beat, or using <a class=\"\" href=\"https:\/\/newatlas.com\/stem-cell-exosomes-hearts-attack-repair\/38325\/\" data-cms-ai=\"0\">stem cell messengers<\/a> to induce the heart to self-repair. Others have identified <a class=\"\" href=\"https:\/\/newatlas.com\/medical\/regenerate-heart-cells-gene-therapy\/\" data-cms-ai=\"0\">transcription factors<\/a> that can get heart cells to begin replicating again.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the University of Houston have demonstrated a new technique for helping heart cells regenerate after a heart attack, using mRNA to return the cells to a stem-cell-like state. Tests in mice showed drastic improvements to heart function a month after a heart attack. Unlike most tissues in the body, heart cells have a [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-140845","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140845","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=140845"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140845\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=140845"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=140845"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=140845"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}