{"id":140420,"date":"2022-06-12T09:01:18","date_gmt":"2022-06-12T14:01:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/06\/scientists-discover-new-molecule-that-kills-hard-to-treat-cancers"},"modified":"2022-06-12T09:01:18","modified_gmt":"2022-06-12T14:01:18","slug":"scientists-discover-new-molecule-that-kills-hard-to-treat-cancers","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/06\/scientists-discover-new-molecule-that-kills-hard-to-treat-cancers","title":{"rendered":"Scientists Discover New Molecule That Kills Hard-to-Treat Cancers"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-discover-new-molecule-that-kills-hard-to-treat-cancers2.jpg\"><\/a><\/p>\n<p>A new molecule synthesized by a University of Texas at Dallas researcher kills a broad spectrum of hard-to-treat cancers, including triple-negative breast cancer, by exploiting a weakness in cells not previously targeted by other drugs.<\/p>\n<p>A <a href=\"https:\/\/www.nature.com\/articles\/s43018-022-00389-8\" target=\"_blank\" rel=\"noopener\" aria-label=\"study, opens new tab\">study<\/a> describing the research \u2014 which was carried out in isolated cells, in human cancer tissue and in human cancers grown in mice \u2014 was published online June 2 in the journal <em>Nature Cancer<\/em>.<\/p>\n<p><a href=\"https:\/\/profiles.utdallas.edu\/jungmo.ahn\">Dr. Jung-Mo Ahn<\/a>, a co-corresponding author of the study and a UT Dallas associate professor of <a href=\"https:\/\/chemistry.utdallas.edu\/\">chemistry and biochemistry<\/a> in the <a href=\"https:\/\/nsm.utdallas.edu\/\">School of Natural Sciences and Mathematics<\/a>, has been passionate about his work designing small molecules that target protein-protein interactions in cells for over a decade. Using an approach called structure-based rational drug design, he previously developed potential therapeutic candidate compounds for treatment-resistant <a href=\"https:\/\/news.utdallas.edu\/health-medicine\/ut-dallas-chemist-focuses-on-drug-resistant-breast\/\">breast cancer<\/a> and for <a href=\"http:\/\/www.utdallas.edu\/news\/2013\/5\/30-24061_Small-Molecule-Could-Have-Big-Impact-on-Prostate-C_article-wide.html\">prostate cancer<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new molecule synthesized by a University of Texas at Dallas researcher kills a broad spectrum of hard-to-treat cancers, including triple-negative breast cancer, by exploiting a weakness in cells not previously targeted by other drugs. A study describing the research \u2014 which was carried out in isolated cells, in human cancer tissue and in human [\u2026]<\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,2229],"tags":[],"class_list":["post-140420","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-mathematics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140420","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=140420"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140420\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=140420"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=140420"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=140420"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}