{"id":140269,"date":"2022-06-08T01:22:20","date_gmt":"2022-06-08T06:22:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/06\/new-crispr-tool-protects-against-viruses-without-making-any-dna-cuts"},"modified":"2022-06-08T01:22:20","modified_gmt":"2022-06-08T06:22:20","slug":"new-crispr-tool-protects-against-viruses-without-making-any-dna-cuts","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/06\/new-crispr-tool-protects-against-viruses-without-making-any-dna-cuts","title":{"rendered":"New CRISPR Tool Protects Against Viruses Without Making Any DNA Cuts"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-crispr-tool-protects-against-viruses-without-making-any-dna-cuts2.jpg\"><\/a><\/p>\n<p><a href=\"https:\/\/www.cell.com\/molecular-cell\/fulltext\/S1097-2765(22)00383-5\">A<\/a> <a href=\"https:\/\/www.cell.com\/molecular-cell\/fulltext\/S1097-2765(22)00383-5\">study<\/a> published last week in <i>Molecular Cell<\/i> took a step towards that radical new concept for CRISPR. Led by Dr. Jennifer Doudna at the University of California Berkeley, who shared a Nobel Prize as a pioneer in the field, the study honed in on Cas9\u2019s less famous and far more enigmatic cousin, Cas12c.<\/p>\n<p>It\u2019s the black sheep of the Cas family. Unlike other members, Cas12c completely lacks the ability to cut DNA. Instead, in bacteria cells, it binds onto invading viruses and protects vulnerable cells without shredding the virus\u2019s DNA. The end result is a powerful antiviral defense system that doesn\u2019t tax the host cell\u2019s inner workings\u2014yet makes it invincible to certain viral infections.<\/p>\n<p>The study shows that chopping up viral DNA isn\u2019t the only route for antiviral defense, at least in bacteria cells, the authors said. But more importantly, we\u2019ve only begun scratching the surface of CRISPR gene editors.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study published last week in Molecular Cell took a step towards that radical new concept for CRISPR. Led by Dr. Jennifer Doudna at the University of California Berkeley, who shared a Nobel Prize as a pioneer in the field, the study honed in on Cas9\u2019s less famous and far more enigmatic cousin, Cas12c. It\u2019s [\u2026]<\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-140269","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140269","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=140269"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140269\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=140269"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=140269"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=140269"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}