{"id":140039,"date":"2022-05-31T23:24:17","date_gmt":"2022-06-01T04:24:17","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/05\/key-to-spreading-inflammation-in-rheumatoid-arthritis-found"},"modified":"2022-05-31T23:24:17","modified_gmt":"2022-06-01T04:24:17","slug":"key-to-spreading-inflammation-in-rheumatoid-arthritis-found","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/05\/key-to-spreading-inflammation-in-rheumatoid-arthritis-found","title":{"rendered":"Key to spreading inflammation in rheumatoid arthritis found"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/OT5AXGS1aL8?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>Remote inflammation in rheumatoid arthritis spreads by neuron crosstalk, and the molecule adenosine triphosphate (ATP) plays a key role in this.<\/p>\n<hr>\n<p>Rheumatoid <a href=\"https:\/\/cosmosmagazine.com\/health\/contrary-to-folklore-alcohol-does-not-help-with-rheumatoid-arthritis\/\" target=\"_blank\" rel=\"noreferrer noopener\">arthritis<\/a> is a chronic inflammatory autoimmune disorder that mainly causes painful joints. It\u2019s estimated to affect <a href=\"https:\/\/www.abs.gov.au\/statistics\/health\/health-conditions-and-risks\/national-health-survey-first-results\/latest-release\" target=\"_blank\" rel=\"noreferrer noopener\">over 450,000 Australians<\/a>.<\/p>\n<p>Remote inflammation is a key feature \u2013 where inflammation spreads from one joint to another. Research has shown that factors involved include cells migrating from the joints and neural circuits, but until now the mechanism behind this spread had not been explained.<\/p>\n<p>Now, a <a href=\"https:\/\/rupress.org\/jem\/article-abstract\/219\/6\/e20212019\/213221\/ATP-spreads-inflammation-to-other-limbs-through?redirectedFrom=fulltext\" target=\"_blank\" rel=\"noreferrer noopener\">new study<\/a> in mice has found that remote inflammation spreads by neuron crosstalk, and that the molecule adenosine triphosphate (ATP) plays a key role in this by acting as a neurotransmitter and inflammation enhancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Remote inflammation in rheumatoid arthritis spreads by neuron crosstalk, and the molecule adenosine triphosphate (ATP) plays a key role in this. Rheumatoid arthritis is a chronic inflammatory autoimmune disorder that mainly causes painful joints. It\u2019s estimated to affect over 450,000 Australians. Remote inflammation is a key feature \u2013 where inflammation spreads from one joint to [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-140039","post","type-post","status-publish","format-standard","hentry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140039","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=140039"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/140039\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=140039"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=140039"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=140039"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}