{"id":138955,"date":"2022-05-04T23:22:38","date_gmt":"2022-05-05T04:22:38","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/05\/lab-grown-brain-experiment-reverses-the-effects-of-autism-linked-gene"},"modified":"2022-05-04T23:22:38","modified_gmt":"2022-05-05T04:22:38","slug":"lab-grown-brain-experiment-reverses-the-effects-of-autism-linked-gene","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/05\/lab-grown-brain-experiment-reverses-the-effects-of-autism-linked-gene","title":{"rendered":"Lab-Grown Brain Experiment Reverses The Effects of Autism-Linked Gene"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/lab-grown-brain-experiment-reverses-the-effects-of-autism-linked-gene3.jpg\"><\/a><\/p>\n<p>Scientists have uncovered changes in neurological structure that could underlie the <a href=\"https:\/\/www.sciencealert.com\/autism-spectrum-disorder\" target=\"_blank\" title=\"autism spectrum disorder\">autism spectrum disorder<\/a> known as <a href=\"https:\/\/pitthopkins.org\/about-pitt-hopkins\/\">Pitt Hopkins syndrome<\/a>, thanks to the help of lab-grown brains developed from human cells.<\/p>\n<p>Furthermore, the researchers were able to recover lost genetic functions through the use of two different gene therapy strategies \u2013 hinting at the possibility of treatments that could one day give those with the condition new options in improving their quality of life.<\/p>\n<p>Pitt Hopkins syndrome is a neurodevelopmental condition stemming from a mutation in a DNA-management gene called transcription factor 4 (<a href=\"https:\/\/medlineplus.gov\/genetics\/gene\/tcf4\/\">TCF4<\/a>). Classed on the <a href=\"https:\/\/www.sciencealert.com\/autism-spectrum-disorder\" target=\"_blank\" title=\"autism\">autism<\/a> spectrum on account of its severe impact on motor skills and sensory integration, it\u2019s a complex condition that presents with a range of severities.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists have uncovered changes in neurological structure that could underlie the autism spectrum disorder known as Pitt Hopkins syndrome, thanks to the help of lab-grown brains developed from human cells. Furthermore, the researchers were able to recover lost genetic functions through the use of two different gene therapy strategies \u2013 hinting at the possibility of [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-138955","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/138955","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=138955"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/138955\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=138955"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=138955"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=138955"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}