{"id":138228,"date":"2022-04-17T07:02:50","date_gmt":"2022-04-17T12:02:50","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/04\/age-products-impact-lifespan-impact-of-hyperglycemia-kidney-function-and-the-microbiome"},"modified":"2022-04-17T07:02:50","modified_gmt":"2022-04-17T12:02:50","slug":"age-products-impact-lifespan-impact-of-hyperglycemia-kidney-function-and-the-microbiome","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/04\/age-products-impact-lifespan-impact-of-hyperglycemia-kidney-function-and-the-microbiome","title":{"rendered":"AGE Products Impact Lifespan: Impact Of Hyperglycemia, Kidney Function, And The Microbiome"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/AB77XCCv3Sg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>Join us on Patreon!<br \/>\n<a href=\"https:\/\/www.patreon.com\/MichaelLustgartenPhD\">https:\/\/www.patreon.com\/MichaelLustgartenPhD<\/a><\/p>\n<p>Papers referenced in the video:<br \/> Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan.<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18599606\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/18599606\/<\/a><\/p>\n<p>Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression.<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17525257\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/17525257\/<\/a><\/p>\n<p>Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N 6-carboxymethyllysine.<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35241804\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35241804\/<\/a><\/p>\n<p>Plasma Carboxymethyl-Lysine, an Advanced Glycation End Product, and All-Cause and Cardiovascular Disease Mortality in Older Community-Dwelling Adults.<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19682127\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/19682127\/<\/a><\/p>\n<p>Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community dwelling women.<\/p>\n<div class=\"more-link-wrapper\"> <a class=\"more-link\" href=\"https:\/\/lifeboat.com\/blog\/2022\/04\/age-products-impact-lifespan-impact-of-hyperglycemia-kidney-function-and-the-microbiome\">Continue reading \u201cAGE Products Impact Lifespan: Impact Of Hyperglycemia, Kidney Function, And The Microbiome\u201d | &gt;<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Join us on Patreon! https:\/\/www.patreon.com\/MichaelLustgartenPhD Papers referenced in the video: Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan. https:\/\/pubmed.ncbi.nlm.nih.gov\/18599606\/ Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression. https:\/\/pubmed.ncbi.nlm.nih.gov\/17525257\/ Gut microbiota drives age-related oxidative stress and mitochondrial damage [\u2026]<\/p>\n","protected":false},"author":587,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-138228","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/138228","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/587"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=138228"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/138228\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=138228"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=138228"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=138228"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}