{"id":138178,"date":"2022-04-15T19:02:32","date_gmt":"2022-04-16T00:02:32","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/04\/in-vivo-partial-reprogramming-alters-age-associated-molecular-changes-during-physiological-aging-in-mice"},"modified":"2022-04-15T19:02:32","modified_gmt":"2022-04-16T00:02:32","slug":"in-vivo-partial-reprogramming-alters-age-associated-molecular-changes-during-physiological-aging-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/04\/in-vivo-partial-reprogramming-alters-age-associated-molecular-changes-during-physiological-aging-in-mice","title":{"rendered":"In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/in-vivo-partial-reprogramming-alters-age-associated-molecular-changes-during-physiological-aging-in-mice.jpg\"><\/a><\/p>\n<p>Age reversal in mice.<\/p>\n<hr>\n<p>In vivo partial reprogramming by expression of Oct4, Sox2, Klf4 and c-Myc has been shown to have rejuvenating effects in a mouse model of premature aging. Here, the authors report that longer-term partial reprogramming regimens are safe and effective in delaying age-related changes in physiologically aged mice.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Age reversal in mice. In vivo partial reprogramming by expression of Oct4, Sox2, Klf4 and c-Myc has been shown to have rejuvenating effects in a mouse model of premature aging. Here, the authors report that longer-term partial reprogramming regimens are safe and effective in delaying age-related changes in physiologically aged mice.<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[269],"tags":[],"class_list":["post-138178","post","type-post","status-publish","format-standard","hentry","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/138178","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=138178"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/138178\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=138178"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=138178"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=138178"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}