{"id":137625,"date":"2022-04-02T12:03:12","date_gmt":"2022-04-02T17:03:12","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/04\/novel-risk-factors-for-arrhythmia-uncovered"},"modified":"2022-04-02T12:03:12","modified_gmt":"2022-04-02T17:03:12","slug":"novel-risk-factors-for-arrhythmia-uncovered","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/04\/novel-risk-factors-for-arrhythmia-uncovered","title":{"rendered":"Novel Risk Factors for Arrhythmia Uncovered"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/novel-risk-factors-for-arrhythmia-uncovered2.jpg\"><\/a><\/p>\n<p>A recent study <a href=\"https:\/\/www.nature.com\/articles\/s41588-021-01007-6\" target=\"_blank\">published<\/a> in <em><i>Nature Genetics<\/i><\/em> identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder associated with sudden death in young adults.<\/p>\n<p>The findings expand possibilities for predictive risk scoring and provide new targets for therapeutic study, according to <a href=\"https:\/\/www.feinberg.northwestern.edu\/faculty-profiles\/az\/profile.html?xid=29140\" target=\"_blank\">Alfred George, Jr., MD<\/a>, chair and the Alfred Newton Richards Professor of <a href=\"http:\/\/www.pharm.northwestern.edu\/\" target=\"_blank\">Pharmacology<\/a> and a co-author of the study.<\/p>\n<p>\u201cPrior to this work, there were only two genomic regions associated with Brugada syndrome risk that were identified by genome-wide studies. Data from the new study greatly expands this to 12 regions with a total of 21 genetic signals to better explain risk for Brugada syndrome,\u201d George said. \u201cThe results also provide the basis for a polygenic risk score that can be used to assess risk in individuals.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder associated with sudden death in young adults. The findings expand possibilities for predictive risk scoring and provide new targets for therapeutic study, according to Alfred George, Jr., MD, chair and the Alfred Newton Richards Professor [\u2026]<\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-137625","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/137625","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=137625"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/137625\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=137625"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=137625"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=137625"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}