{"id":137461,"date":"2022-03-29T09:22:34","date_gmt":"2022-03-29T16:22:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/03\/enzyme-blocker-could-open-new-treatments-for-neurodegenerative-diseases"},"modified":"2022-03-29T09:22:34","modified_gmt":"2022-03-29T16:22:34","slug":"enzyme-blocker-could-open-new-treatments-for-neurodegenerative-diseases","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/03\/enzyme-blocker-could-open-new-treatments-for-neurodegenerative-diseases","title":{"rendered":"Enzyme blocker could open new treatments for neurodegenerative diseases"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/enzyme-blocker-could-open-new-treatments-for-neurodegenerative-diseases2.jpg\"><\/a><\/p>\n<p>\ud835\udc0d\ud835\udc1e\ud835\udc30 \ud835\udc00\ud835\udc2d\ud835\udc25\ud835\udc1a\ud835\udc2c:<\/p>\n<p>The Neuro-Network.<\/p>\n<p>\ud835\udc04\ud835\udc27\ud835\udc33\ud835\udc32\ud835\udc26\ud835\udc1e \ud835\udc1b\ud835\udc25\ud835\udc28\ud835\udc1c\ud835\udc24\ud835\udc1e\ud835\udc2b \ud835\udc1c\ud835\udc28\ud835\udc2e\ud835\udc25\ud835\udc1d \ud835\udc28\ud835\udc29\ud835\udc1e\ud835\udc27 \ud835\udc27\ud835\udc1e\ud835\udc30 \ud835\udc2d\ud835\udc2b\ud835\udc1e\ud835\udc1a\ud835\udc2d\ud835\udc26\ud835\udc1e\ud835\udc27\ud835\udc2d\ud835\udc2c \ud835\udc1f\ud835\udc28\ud835\udc2b \ud835\udc27\ud835\udc1e\ud835\udc2e\ud835\udc2b\ud835\udc28\ud835\udc1d\ud835\udc1e\ud835\udc20\ud835\udc1e\ud835\udc27\ud835\udc1e\ud835\udc2b\ud835\udc1a\ud835\udc2d\ud835\udc22\ud835\udc2f\ud835\udc1e \ud835\udc1d\ud835\udc22\ud835\udc2c\ud835\udc1e\ud835\udc1a\ud835\udc2c\ud835\udc1e\ud835\udc2c<\/p>\n<p>\ud835\ude4d\ud835\ude5a\ud835\ude68\ud835\ude5a\ud835\ude56\ud835\ude67\ud835\ude58\ud835\ude5d\ud835\ude5a\ud835\ude67\ud835\ude68 \ud835\ude5d\ud835\ude56\ud835\ude6b\ud835\ude5a \ud835\ude6a\ud835\ude63\ud835\ude58\ud835\ude64\ud835\ude6b\ud835\ude5a\ud835\ude67\ud835\ude5a\ud835\ude59 \ud835\ude5d\ud835\ude64\ud835\ude6c \ud835\ude56 \ud835\ude58\ud835\ude5a\ud835\ude67\ud835\ude69\ud835\ude56\ud835\ude5e\ud835\ude63 \ud835\ude62\ud835\ude64\ud835\ude61\ud835\ude5a\ud835\ude58\ud835\ude6a\ud835\ude61\ud835\ude56\ud835\ude67 \ud835\ude65\ud835\ude56\ud835\ude69\ud835\ude5d\ud835\ude6c\ud835\ude56\ud835\ude6e \ud835\ude69\ud835\ude67\ud835\ude5e\ud835\ude5c\ud835\ude5c\ud835\ude5a\ud835\ude67\ud835\ude68 \ud835\ude69\ud835\ude5d\ud835\ude5a \ud835\ude57\ud835\ude67\ud835\ude5a\ud835\ude56\ud835\ude60\ud835\ude59\ud835\ude64\ud835\ude6c\ud835\ude63 \ud835\ude64\ud835\ude5b \ud835\ude63\ud835\ude5a\ud835\ude67\u2026 See more.<\/p>\n<hr>\n<p>Researchers have uncovered how a certain molecular pathway triggers the breakdown of nerve fibers in neurodegenerative diseases \u2013 and more importantly, how to potentially switch it off. The find could lead to a new class of drugs that slows the progression of these debilitating disorders.<\/p>\n<p>The focus of the study was an enzyme called SARM1, which is expressed in neurons and plays a role as an immune regulator. However, it also functions as a sensor of metabolic stress, and at a certain point it sparks a cascade of processes that eventually begins to break down axons, leading to some of the issues associated with Parkinson\u2019s disease, ALS, neuropathy, and other neurodegenerative diseases.<\/p>\n<div class=\"more-link-wrapper\"> <a class=\"more-link\" href=\"https:\/\/lifeboat.com\/blog\/2022\/03\/enzyme-blocker-could-open-new-treatments-for-neurodegenerative-diseases\">Continue reading \u201cEnzyme blocker could open new treatments for neurodegenerative diseases\u201d | &gt;<\/a><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\ud835\udc0d\ud835\udc1e\ud835\udc30 \ud835\udc00\ud835\udc2d\ud835\udc25\ud835\udc1a\ud835\udc2c: The Neuro-Network. \ud835\udc04\ud835\udc27\ud835\udc33\ud835\udc32\ud835\udc26\ud835\udc1e \ud835\udc1b\ud835\udc25\ud835\udc28\ud835\udc1c\ud835\udc24\ud835\udc1e\ud835\udc2b \ud835\udc1c\ud835\udc28\ud835\udc2e\ud835\udc25\ud835\udc1d \ud835\udc28\ud835\udc29\ud835\udc1e\ud835\udc27 \ud835\udc27\ud835\udc1e\ud835\udc30 \ud835\udc2d\ud835\udc2b\ud835\udc1e\ud835\udc1a\ud835\udc2d\ud835\udc26\ud835\udc1e\ud835\udc27\ud835\udc2d\ud835\udc2c \ud835\udc1f\ud835\udc28\ud835\udc2b \ud835\udc27\ud835\udc1e\ud835\udc2e\ud835\udc2b\ud835\udc28\ud835\udc1d\ud835\udc1e\ud835\udc20\ud835\udc1e\ud835\udc27\ud835\udc1e\ud835\udc2b\ud835\udc1a\ud835\udc2d\ud835\udc22\ud835\udc2f\ud835\udc1e \ud835\udc1d\ud835\udc22\ud835\udc2c\ud835\udc1e\ud835\udc1a\ud835\udc2c\ud835\udc1e\ud835\udc2c \ud835\ude4d\ud835\ude5a\ud835\ude68\ud835\ude5a\ud835\ude56\ud835\ude67\ud835\ude58\ud835\ude5d\ud835\ude5a\ud835\ude67\ud835\ude68 \ud835\ude5d\ud835\ude56\ud835\ude6b\ud835\ude5a \ud835\ude6a\ud835\ude63\ud835\ude58\ud835\ude64\ud835\ude6b\ud835\ude5a\ud835\ude67\ud835\ude5a\ud835\ude59 \ud835\ude5d\ud835\ude64\ud835\ude6c \ud835\ude56 \ud835\ude58\ud835\ude5a\ud835\ude67\ud835\ude69\ud835\ude56\ud835\ude5e\ud835\ude63 \ud835\ude62\ud835\ude64\ud835\ude61\ud835\ude5a\ud835\ude58\ud835\ude6a\ud835\ude61\ud835\ude56\ud835\ude67 \ud835\ude65\ud835\ude56\ud835\ude69\ud835\ude5d\ud835\ude6c\ud835\ude56\ud835\ude6e \ud835\ude69\ud835\ude67\ud835\ude5e\ud835\ude5c\ud835\ude5c\ud835\ude5a\ud835\ude67\ud835\ude68 \ud835\ude69\ud835\ude5d\ud835\ude5a \ud835\ude57\ud835\ude67\ud835\ude5a\ud835\ude56\ud835\ude60\ud835\ude59\ud835\ude64\ud835\ude6c\ud835\ude63 \ud835\ude64\ud835\ude5b \ud835\ude63\ud835\ude5a\ud835\ude67\u2026 See more. Researchers have uncovered how a certain molecular pathway triggers the breakdown of nerve fibers in neurodegenerative diseases \u2013 and more importantly, how to potentially switch it off. [\u2026]<\/p>\n","protected":false},"author":461,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-137461","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/137461","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/461"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=137461"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/137461\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=137461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=137461"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=137461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}