{"id":136331,"date":"2022-03-03T05:01:34","date_gmt":"2022-03-03T13:01:34","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/03\/what-might-explain-huntingtons-disease"},"modified":"2022-03-03T05:01:34","modified_gmt":"2022-03-03T13:01:34","slug":"what-might-explain-huntingtons-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/03\/what-might-explain-huntingtons-disease","title":{"rendered":"What might explain Huntington\u2019s Disease?"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/what-might-explain-huntingtons-disease.jpg\"><\/a><\/p>\n<p>Could 2 B vitamins help those suffering with Huntington\u2019s Disease?<\/p>\n<hr>\n<p>T he Huntington\u2019s disease (HD) community has recently experienced <a href=\"https:\/\/dnascience.plos.org\/2021\/04\/08\/huntingtons-disease-2-steps-backward-1-step-forward\/\" target=\"_blank\" rel=\"noopener\">setbacks<\/a>, but a new research report may reignite hope, from an unexpected source: the vitamin thiamine (B1), with help from biotin (B7). The investigators, from several institutions in Spain and UCLA, write in <a href=\"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.abe7104\" target=\"_blank\" rel=\"noopener\">Science Translational Medicine<\/a>, \u201cTogether, these results demonstrate a thiamine deficiency in HD brain and suggest that individuals with HD might benefit from thiamine and\/or biotin supplementation therapy.\u201d<\/p>\n<p>Health care providers may suggest certain supplements for HD patients, based perhaps on a deficiency (vitamins C, B12, E) in the blood, or for general health. But the new findings are different. The researchers didn\u2019t set out to detect a vitamin deficiency, but instead probed the messaging within cells in the HD brain, which led them to a biochemical juncture that revealed the thiamine\/biotin connection.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Could 2 B vitamins help those suffering with Huntington\u2019s Disease? T he Huntington\u2019s disease (HD) community has recently experienced setbacks, but a new research report may reignite hope, from an unexpected source: the vitamin thiamine (B1), with help from biotin (B7). The investigators, from several institutions in Spain and UCLA, write in Science Translational Medicine, [\u2026]<\/p>\n","protected":false},"author":667,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,1495,47],"tags":[],"class_list":["post-136331","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/136331","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/667"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=136331"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/136331\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=136331"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=136331"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=136331"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}