{"id":134378,"date":"2022-01-20T00:23:25","date_gmt":"2022-01-20T08:23:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/01\/new-virus-like-particles-can-deliver-crispr-to-any-cell-in-the-body"},"modified":"2022-01-20T00:23:25","modified_gmt":"2022-01-20T08:23:25","slug":"new-virus-like-particles-can-deliver-crispr-to-any-cell-in-the-body","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/01\/new-virus-like-particles-can-deliver-crispr-to-any-cell-in-the-body","title":{"rendered":"New Virus-Like Particles Can Deliver CRISPR to Any Cell in the Body"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-virus-like-particles-can-deliver-crispr-to-any-cell-in-the-body2.jpg\"><\/a><\/p>\n<p>One critical difference? Unlike a Mars mission\u2019s \u201c<a href=\"https:\/\/singularityhub.com\/2021\/02\/18\/7-minutes-of-terror-the-technology-perseverance-will-need-to-survive-landing-on-mars\/\">seven minutes of terror<\/a>,\u201d during which the entry, descent, and landing occur too fast for human operators to interfere, gene therapy delivery is completely blind. Once inside the body, the entire flight sequence rests solely on the design of the carrier \u201cspaceship.\u201d<\/p>\n<p>In other words, for gene therapy to work efficiently, smarter carriers are imperative.<\/p>\n<p>This month, a team at Harvard led by Dr. David Liu <a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(21)01484-7?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867421014847%3Fshowall%3Dtrue#secsectitle0095\">launched a new generation<\/a> of molecular carriers inspired by viruses. Dubbed engineered virus-like particles (eVLPs), these bubble-like carriers can deliver <a href=\"https:\/\/singularityhub.com\/tag\/crispr\/\">CRISPR<\/a> and base editing components to a myriad of organs with minimal side effects.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>One critical difference? Unlike a Mars mission\u2019s \u201cseven minutes of terror,\u201d during which the entry, descent, and landing occur too fast for human operators to interfere, gene therapy delivery is completely blind. Once inside the body, the entire flight sequence rests solely on the design of the carrier \u201cspaceship.\u201d In other words, for gene therapy [\u2026]<\/p>\n","protected":false},"author":628,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,1514],"tags":[],"class_list":["post-134378","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-space-travel"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/134378","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/628"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=134378"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/134378\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=134378"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=134378"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=134378"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}