{"id":133790,"date":"2022-01-09T03:22:38","date_gmt":"2022-01-09T11:22:38","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/01\/the-science-behind-why-we-age-lifespan-with-dr-david-sinclair-1"},"modified":"2022-01-09T03:22:38","modified_gmt":"2022-01-09T11:22:38","slug":"the-science-behind-why-we-age-lifespan-with-dr-david-sinclair-1","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/01\/the-science-behind-why-we-age-lifespan-with-dr-david-sinclair-1","title":{"rendered":"The Science Behind Why We Age | Lifespan with Dr. David Sinclair #1"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/X1kLizzdb2c?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>Sinclair\u2019s first episode. Enjoy.<\/p>\n<hr>\n<p>In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic regulators of aging, the process of \u201cex-differentiation\u201d in which cells begin to lose their identity, and how all of this makes up the \u201cInformation Theory of Aging\u201d, and the difference between \u201cbiological age\u201d and \u201cchronological age\u201d and how we can measure biological age through DNA methylation clocks.<\/p>\n<p>Thank you to our sponsors:<br \/> Athletic Greens \u2014 <a href=\"https:\/\/athleticgreens.com\/sinclair\">https:\/\/athleticgreens.com\/sinclair<\/a>.<br \/> InsideTracker \u2014 <a href=\"https:\/\/insidetracker.com\/sinclair\">https:\/\/insidetracker.com\/sinclair<\/a>.<br \/> Levels \u2014 <a href=\"https:\/\/levels.link\/sinclair\">https:\/\/levels.link\/sinclair<\/a>.<\/p>\n<p>Our Patreon page:<br \/>\n<a href=\"https:\/\/www.patreon.com\/davidsinclair\">https:\/\/www.patreon.com\/davidsinclair<\/a>.<\/p>\n<p>Lifespan book:<\/p>\n<div class=\"more-link-wrapper\"> <a class=\"more-link\" href=\"https:\/\/lifeboat.com\/blog\/2022\/01\/the-science-behind-why-we-age-lifespan-with-dr-david-sinclair-1\">Continue reading \u201cThe Science Behind Why We Age | Lifespan with Dr. David Sinclair #1\u201d | &gt;<\/a><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sinclair\u2019s first episode. Enjoy. In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic regulators of aging, the process of \u201cex-differentiation\u201d in which cells begin to [\u2026]<\/p>\n","protected":false},"author":388,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,1496,269,224],"tags":[],"class_list":["post-133790","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-law","category-life-extension","category-science"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/133790","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/388"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=133790"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/133790\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=133790"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=133790"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=133790"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}