{"id":133774,"date":"2022-01-08T16:22:40","date_gmt":"2022-01-09T00:22:40","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/01\/3d-bioprinted-tissues-can-now-be-stored-in-the-freezer-until-needed"},"modified":"2022-01-08T16:22:40","modified_gmt":"2022-01-09T00:22:40","slug":"3d-bioprinted-tissues-can-now-be-stored-in-the-freezer-until-needed","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/01\/3d-bioprinted-tissues-can-now-be-stored-in-the-freezer-until-needed","title":{"rendered":"3D-bioprinted tissues can now be stored in the freezer until needed"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/DyHTRwTUy-Q?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>A major obstacle to widespread study and clinical use of 3D tissues is their short shelf-life, which may be anywhere from a just few hours to a few days. As in the case of an organ transplant, a bioprinted tissue must be transported rapidly to the location where it is needed, or it will not be viable. In the journal <em>Matter<\/em> on December 21<sup>st<\/sup>, researchers at Brigham and Women\u2019s Hospital and Harvard Medical School describe their work combining 3D bioprinting with cryopreservative techniques to create tissues which can be preserved in a freezer at-196\u00b0C and thawed within minutes for immediate use.<\/p>\n<p>\u201cFor conventional bioprinting, there is basically no shelf life. It\u2019s really just print, and then use, in most cases,\u201d says lead author Y. Shrike Zhang (<a href=\"https:\/\/twitter.com\/shrikezhang\">@shrikezhang<\/a>), a biomedical engineer at Brigham and Women\u2019s Hospital. \u201cWith cryobioprinting, you can print and store in the frozen state for basically as long as you want.\u201d<\/p>\n<p>The use of 3D bioprinting to create artificial human tissue first appeared twenty years ago. As in conventional 3D printing, an ink is extruded layer by layer through a nozzle into a pre-specified shape. In the case of bioprinting, the ink is typically made up of a gelatin-like scaffolding embedded with living cells. Cryobioprinting works the same way, except the printing is performed directly onto a cold plate held at temperatures down to-20\u00b0C. After the tissues are printed, they are immediately moved to cryogenic conditions for long-term storage.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A major obstacle to widespread study and clinical use of 3D tissues is their short shelf-life, which may be anywhere from a just few hours to a few days. As in the case of an organ transplant, a bioprinted tissue must be transported rapidly to the location where it is needed, or it will not [\u2026]<\/p>\n","protected":false},"author":367,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1489,1503,11],"tags":[],"class_list":["post-133774","post","type-post","status-publish","format-standard","hentry","category-3d-printing","category-bioprinting","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/133774","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/367"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=133774"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/133774\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=133774"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=133774"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=133774"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}