{"id":133730,"date":"2022-01-07T18:22:26","date_gmt":"2022-01-08T02:22:26","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2022\/01\/new-way-to-alter-dna-affect-health-circumvents-gut-bacteria"},"modified":"2022-01-07T18:22:26","modified_gmt":"2022-01-08T02:22:26","slug":"new-way-to-alter-dna-affect-health-circumvents-gut-bacteria","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2022\/01\/new-way-to-alter-dna-affect-health-circumvents-gut-bacteria","title":{"rendered":"New way to alter DNA, affect health circumvents gut bacteria"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-way-to-alter-dna-affect-health-circumvents-gut-bacteria.jpg\"><\/a><\/p>\n<p>Our gut microbiome helps us out every day by processing the fiber we can\u2019t digest. The bacteria ferment the fiber into key chemicals known as short-chain fatty acids, or SCFAs, that are essential for human health. SCFAs fight inflammation, help kill dangerous bacteria, protect the lining of the gut, and can even help prevent cancer.<\/p>\n<p>In a new study, the John Denu lab at the University of Wisconsin-Madison\u2019s Wisconsin Institute for Discovery has learned that the fatty acids butyrate and propionate also activate p300, a crucial human enzyme that promotes the unspooling of DNA. This unwound DNA allows more genes to become active and expressed, which ultimately affects human health.<\/p>\n<hr>\n<p>A study by Wisconsin Institute for Discovery researchers challenges long-held beliefs, with potential implications for physiological processes and diseases such as propionic acidemia, autism spectrum disorder and Alzheimer\u2019s disease.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our gut microbiome helps us out every day by processing the fiber we can\u2019t digest. The bacteria ferment the fiber into key chemicals known as short-chain fatty acids, or SCFAs, that are essential for human health. SCFAs fight inflammation, help kill dangerous bacteria, protect the lining of the gut, and can even help prevent cancer. [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,1495,47],"tags":[],"class_list":["post-133730","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/133730","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=133730"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/133730\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=133730"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=133730"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=133730"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}