{"id":131974,"date":"2021-12-08T01:24:39","date_gmt":"2021-12-08T09:24:39","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/12\/unusual-quadruple-helix-structure-in-dna-may-be-behind-rare-aging-syndrome"},"modified":"2021-12-08T01:24:39","modified_gmt":"2021-12-08T09:24:39","slug":"unusual-quadruple-helix-structure-in-dna-may-be-behind-rare-aging-syndrome","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/12\/unusual-quadruple-helix-structure-in-dna-may-be-behind-rare-aging-syndrome","title":{"rendered":"Unusual \u2018Quadruple Helix\u2019 Structure in DNA May Be Behind Rare Aging Syndrome"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/unusual-quadruple-helix-structure-in-dna-may-be-behind-rare-aging-syndrome3.jpg\"><\/a><\/p>\n<p>The double-helix structure has practically become synonymous with DNA, but it isn\u2019t the only way long strands of genetic information squeeze themselves into a tight space.<\/p>\n<p>When a double-strand of DNA doubles back on itself or attaches to another double-strand, it can actually create a quadruple-stranded knot, known as a G-quadruplex.<\/p>\n<p>Scientists <a href=\"https:\/\/www.nature.com\/articles\/nchem.1548\" target=\"_blank\" rel=\"noopener noreferrer\">first discovered<\/a> these \u2018double-double-helixes\u2019 in living human cells in 2013, and in the years since, these knots have been found in <a href=\"https:\/\/www.sciencealert.com\/rare-4-stranded-dna-has-been-observed-in-action-for-the-first-time\" target=\"_blank\" rel=\"noopener noreferrer\">high concentrations<\/a> in cancerous cells.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The double-helix structure has practically become synonymous with DNA, but it isn\u2019t the only way long strands of genetic information squeeze themselves into a tight space. When a double-strand of DNA doubles back on itself or attaches to another double-strand, it can actually create a quadruple-stranded knot, known as a G-quadruplex. Scientists first discovered these [\u2026]<\/p>\n","protected":false},"author":359,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-131974","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/131974","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/359"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=131974"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/131974\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=131974"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=131974"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=131974"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}