{"id":131183,"date":"2021-11-24T19:23:52","date_gmt":"2021-11-25T03:23:52","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/11\/enhancing-the-workhorse-artificial-intelligence-hardware-innovations-boost-confocal-microscopes-performance"},"modified":"2021-11-24T19:23:52","modified_gmt":"2021-11-25T03:23:52","slug":"enhancing-the-workhorse-artificial-intelligence-hardware-innovations-boost-confocal-microscopes-performance","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/11\/enhancing-the-workhorse-artificial-intelligence-hardware-innovations-boost-confocal-microscopes-performance","title":{"rendered":"Enhancing the workhorse: Artificial intelligence, hardware innovations boost confocal microscope\u2019s performance"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/enhancing-the-workhorse-artificial-intelligence-hardware-innovations-boost-confocal-microscopes-performance3.jpg\"><\/a><\/p>\n<p>Since artificial intelligence pioneer Marvin Minsky patented the principle of confocal microscopy in 1957, it has become the workhorse standard in life science laboratories worldwide, due to its superior contrast over traditional wide-field microscopy. Yet confocal microscopes aren\u2019t perfect. They boost resolution by imaging just one, single, in-focus point at a time, so it can take quite a while to scan an entire, delicate biological sample, exposing it light dosages that can be toxic.<\/p>\n<p>To push confocal imaging to an unprecedented level of performance, a collaboration at the Marine Biological Laboratory (MBL) has invented a \u201ckitchen sink\u201d confocal platform that borrows solutions from other high-powered imaging systems, adds a unifying thread of \u201cDeep Learning\u201d artificial intelligence algorithms, and successfully improves the confocal\u2019s volumetric resolution by more than 10-fold while simultaneously reducing phototoxicity. Their report on the technology, called \u201cMultiview Confocal Super-Resolution Microscopy,\u201d is published online this week in <i>Nature.<\/i><\/p>\n<p>\u201cMany labs have confocals, and if they can eke more performance out of them using these artificial intelligence algorithms, then they don\u2019t have to invest in a whole new microscope. To me, that\u2019s one of the best and most exciting reasons to adopt these AI methods,\u201d said senior author and MBL Fellow Hari Shroff of the National Institute of Biomedical Imaging and Bioengineering.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Since artificial intelligence pioneer Marvin Minsky patented the principle of confocal microscopy in 1957, it has become the workhorse standard in life science laboratories worldwide, due to its superior contrast over traditional wide-field microscopy. Yet confocal microscopes aren\u2019t perfect. They boost resolution by imaging just one, single, in-focus point at a time, so it can [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,1506,41,6],"tags":[],"class_list":["post-131183","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-food","category-information-science","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/131183","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=131183"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/131183\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=131183"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=131183"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=131183"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}