{"id":131126,"date":"2021-11-23T13:23:22","date_gmt":"2021-11-23T21:23:22","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/11\/sars-cov-2-gene-content-and-covid-19-mutation-impact"},"modified":"2021-11-23T13:23:22","modified_gmt":"2021-11-23T21:23:22","slug":"sars-cov-2-gene-content-and-covid-19-mutation-impact","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/11\/sars-cov-2-gene-content-and-covid-19-mutation-impact","title":{"rendered":"SARS-CoV-2 gene content and COVID-19 mutation impact"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/sars-cov-2-gene-content-and-covid-19-mutation-impact.jpg\"><\/a><\/p>\n<p>The SARS-CoV-2 gene set remains unresolved, hindering dissection of COVID-19 biology. Comparing 44 <i>Sarbecovirus<\/i> genomes provides a high-confidence protein-coding gene set. The study characterizes protein-level and nucleotide-level evolutionary constraints, and prioritizes <i>functional<\/i> mutations from the ongoing COVID-19 pandemic.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The SARS-CoV-2 gene set remains unresolved, hindering dissection of COVID-19 biology. Comparing 44 Sarbecovirus genomes provides a high-confidence protein-coding gene set. The study characterizes protein-level and nucleotide-level evolutionary constraints, and prioritizes functional mutations from the ongoing COVID-19 pandemic.<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,11,412],"tags":[],"class_list":["post-131126","post","type-post","status-publish","format-standard","hentry","category-biological","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/131126","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=131126"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/131126\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=131126"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=131126"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=131126"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}