{"id":130757,"date":"2021-11-17T10:23:57","date_gmt":"2021-11-17T18:23:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/11\/ai-can-now-model-the-molecular-machines-that-govern-all-life"},"modified":"2021-11-17T10:23:57","modified_gmt":"2021-11-17T18:23:57","slug":"ai-can-now-model-the-molecular-machines-that-govern-all-life","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/11\/ai-can-now-model-the-molecular-machines-that-govern-all-life","title":{"rendered":"AI Can Now Model the Molecular Machines That Govern All Life"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/ai-can-now-model-the-molecular-machines-that-govern-all-life2.jpg\"><\/a><\/p>\n<p>This month, the UW team <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.abm4805\">upped their game<\/a>.<\/p>\n<p>Tapping into both AlphaFold and RoseTTAFold, they tweaked the programs to predict which proteins are likely to tag-team and sketched up the resulting complexes into a 3D models.<\/p>\n<p>Using AI, the team predicted hundreds of complexes\u2014many of which are entirely new\u2014that regulate DNA repair, govern the cell\u2019s digestive system, and perform other critical biological functions. These under-the-hood insights could impact the next generation of DNA editors and spur new treatments for neurodegenerative disorders or anti-aging therapies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This month, the UW team upped their game. Tapping into both AlphaFold and RoseTTAFold, they tweaked the programs to predict which proteins are likely to tag-team and sketched up the resulting complexes into a 3D models. Using AI, the team predicted hundreds of complexes\u2014many of which are entirely new\u2014that regulate DNA repair, govern the cell\u2019s [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,4,6],"tags":[],"class_list":["post-130757","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-nanotechnology","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/130757","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=130757"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/130757\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=130757"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=130757"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=130757"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}