{"id":129364,"date":"2021-10-22T00:22:23","date_gmt":"2021-10-22T07:22:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/10\/gene-editing-can-turn-storage-fat-cells-into-energy-burning-fat-cells"},"modified":"2021-10-22T00:22:23","modified_gmt":"2021-10-22T07:22:23","slug":"gene-editing-can-turn-storage-fat-cells-into-energy-burning-fat-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/10\/gene-editing-can-turn-storage-fat-cells-into-energy-burning-fat-cells","title":{"rendered":"Gene editing can turn storage fat cells into energy-burning fat cells"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/gene-editing-can-turn-storage-fat-cells-into-energy-burning-fat-cells.jpg\"><\/a><\/p>\n<p>A team of researchers at UT Southwestern Medical Center\u2019s Touchstone Diabetes Center have successfully used CRISPR gene editing to turn fat cells normally used for storage into energy-burning cells.<\/p>\n<p>\u201cIt\u2019s like flipping a switch. We removed the \u2018brake\u2019 on the energy burning pathway in <a href=\"https:\/\/medicalxpress.com\/tags\/fat+cells\/\" rel=\"tag\" class=\"\">fat cells<\/a> by engineering a mutation that disrupts the interaction between a single pair of proteins,\u201d said study leader Rana Gupta, Ph.D., Associate Professor of Internal Medicine. \u201cOur research demonstrates that releasing this brake in fat cells can potentially help make existing <a href=\"https:\/\/medicalxpress.com\/tags\/diabetes+medications\/\" rel=\"tag\" class=\"\">diabetes medications<\/a> much more effective.\u201d<\/p>\n<p>The research at UT Southwestern, ranked as one of the nation\u2019s top 25 hospitals for diabetes and endocrinology care, is published in <i>Genes and Development<\/i> and supported by the National Institutes of Health.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of researchers at UT Southwestern Medical Center\u2019s Touchstone Diabetes Center have successfully used CRISPR gene editing to turn fat cells normally used for storage into energy-burning cells. \u201cIt\u2019s like flipping a switch. We removed the \u2018brake\u2019 on the energy burning pathway in fat cells by engineering a mutation that disrupts the interaction between [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412,1495],"tags":[],"class_list":["post-129364","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/129364","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=129364"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/129364\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=129364"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=129364"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=129364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}