{"id":129263,"date":"2021-10-20T11:22:33","date_gmt":"2021-10-20T18:22:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/10\/in-a-first-surgeons-attached-a-pig-kidney-to-a-human-and-it-worked"},"modified":"2021-10-20T11:22:33","modified_gmt":"2021-10-20T18:22:33","slug":"in-a-first-surgeons-attached-a-pig-kidney-to-a-human-and-it-worked","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/10\/in-a-first-surgeons-attached-a-pig-kidney-to-a-human-and-it-worked","title":{"rendered":"In a First, Surgeons Attached a Pig Kidney to a Human \u2014 and It Worked"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/in-a-first-surgeons-attached-a-pig-kidney-to-a-human-and-it-worked2.jpg\"><\/a><\/p>\n<p>The kidney used in the new procedure was obtained by knocking out a pig gene that encodes a sugar molecule that elicits an aggressive human rejection response. The pig was genetically engineered by Revivicor and approved by the Food and Drug Administration for use as a source for human therapeutics.<\/p>\n<p>Dr. Montgomery and his team also transplanted the pig\u2019s thymus, a gland that is involved in the immune system, in an effort to ward off immune reactions to the kidney.<\/p>\n<p>After attaching the kidney to blood vessels in the upper leg, the surgeons covered it with a protective shield so they could observe it and take tissue samples over the 54-hour study period. Urine and creatinine levels were normal, Dr. Montgomery and his colleagues found, and no signs of rejection were detected during more than two days of observation.<\/p>\n<hr>\n<p>A kidney grown in a genetically altered pig seemed to function normally, potentially a new source for desperately needed transplant organs.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The kidney used in the new procedure was obtained by knocking out a pig gene that encodes a sugar molecule that elicits an aggressive human rejection response. The pig was genetically engineered by Revivicor and approved by the Food and Drug Administration for use as a source for human therapeutics. Dr. Montgomery and his team [\u2026]<\/p>\n","protected":false},"author":474,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-129263","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/129263","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/474"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=129263"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/129263\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=129263"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=129263"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=129263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}