{"id":127843,"date":"2021-09-19T10:24:33","date_gmt":"2021-09-19T17:24:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/09\/the-crispr-family-tree-holds-a-multitude-of-untapped-gene-editing-tools"},"modified":"2021-09-19T10:24:33","modified_gmt":"2021-09-19T17:24:33","slug":"the-crispr-family-tree-holds-a-multitude-of-untapped-gene-editing-tools","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/09\/the-crispr-family-tree-holds-a-multitude-of-untapped-gene-editing-tools","title":{"rendered":"The CRISPR Family Tree Holds a Multitude of Untapped Gene Editing Tools"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/the-crispr-family-tree-holds-a-multitude-of-untapped-gene-editing-tools3.jpg\"><\/a><\/p>\n<p>Thanks to <a href=\"https:\/\/singularityhub.com\/tag\/crispr\/\">CRISPR<\/a>, gene therapy and \u201cdesigner babies\u201d are now a reality. The gene editing Swiss army knife is one of the most impactful biomedical discoveries of the last decade. Now <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.abj6856?_ga=2.173670755.1543405839.1631031519-903201786.1555897465\">a new study<\/a> suggests we\u2019ve just begun dipping our toes into the <a href=\"https:\/\/singularityhub.com\/2021\/09\/05\/new-mini-crispr-systems-could-dramatically-expand-the-scope-of-gene-therapy\/\">CRISPR<\/a> pond.<\/p>\n<p>CRISPR-Cas9 comes from lowly origins. It was first discovered as a natural mechanism in bacteria and yeast cells to help fight off invading viruses. This led Dr. Feng Zhang, one of the pioneers of the technology, to ask: where did this system evolve from? Are there any other branches of the CRISPR family tree that we can also harness for gene editing?<\/p>\n<p>In a new paper published last week in <i>Science<\/i>, Zhang\u2019s team traced the origins of CRISPR to unveil a vast universe of potential gene editing tools. As \u201ccousins\u201d of <a href=\"https:\/\/singularityhub.com\/2021\/07\/01\/breakthrough-crispr-gene-therapy-could-be-a-one-and-done-injection\/\">CRISPR<\/a>, these new proteins can readily snip targeted genes inside Petri dishes, similar to their famous relative.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thanks to CRISPR, gene therapy and \u201cdesigner babies\u201d are now a reality. The gene editing Swiss army knife is one of the most impactful biomedical discoveries of the last decade. Now a new study suggests we\u2019ve just begun dipping our toes into the CRISPR pond. CRISPR-Cas9 comes from lowly origins. It was first discovered as [\u2026]<\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11],"tags":[],"class_list":["post-127843","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/127843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=127843"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/127843\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=127843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=127843"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=127843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}